104849-08-3

Basic information

• Product Name: N-(benzyloxycarbonyl)-L-phenylalanyl-D-alanyl-L-2-amino-7-(tert-butyloxycarbonyl)heptanoyl-D-proline methyl ester
• Synonyms: N-(benzyloxycarbonyl)-L-phenylalanyl-D-alanyl-L-2-amino-7-(tert-butyloxycarbonyl)heptanoyl-D-proline methyl ester
• CAS NO: 104849-08-3
• Molecular Weight: 708.852
• Mol File: 104849-08-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(benzyloxycarbonyl)-L-phenylalanyl-D-alanyl-L-2-amino-7-(tert-butyloxycarbonyl)heptanoyl-D-proline methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(benzyloxycarbonyl)-L-phenylalanyl-D-alanyl-L-2-amino-7-(tert-butyloxycarbonyl)heptanoyl-D-proline methyl ester(104849-08-3)
• EPA Substance Registry System: N-(benzyloxycarbonyl)-L-phenylalanyl-D-alanyl-L-2-amino-7-(tert-butyloxycarbonyl)heptanoyl-D-proline methyl ester(104849-08-3)

Safety Data

• Hazardous Substances Data: 104849-08-3(Hazardous Substances Data)

Upstream product

• 2578-84-9 N-benzyloxycarbonyl-L-phenylalanine p-nitrophenyl ester 
• 104848-90-0 CH₃CO₂^(1-)*H₃N-D-Ala-Asu(O^tBu)-D-Pro-OMe⁽¹⁺⁾ 

Downstream Products

• 104849-09-4 N-(benzyloxycarbonyl)-L-phenylalanyl-D-alanyl-L-2-amino-7-(tert-butyloxycarbonyl)heptanoyl-D-proline 
• 104849-11-8 L-phenylalanyl-D-alanyl-L-2-amino-7-(tert-butyloxycarbonyl)heptanoyl-D-proline acetate salt 
• 104994-59-4 6-((5S,8R,11S,13aR)-11-Benzyl-8-methyl-4,7,10,13-tetraoxo-tetradecahydro-3a,6,9,12-tetraaza-cyclopentacyclododecen-5-yl)-hexanoic acid 
• 104849-14-1 cyclo 
• 104849-13-0 (5S,8R,11S,13aR)-11-Benzyl-5-(7-diazo-6-oxo-heptyl)-8-methyl-decahydro-3a,6,9,12-tetraaza-cyclopentacyclododecene-4,7,10,13-tetraone 
• 104849-12-9 cyclo 
• 104849-12-9 6-((5S,8R,13aR)-11-Benzyl-8-methyl-4,7,10,13-tetraoxo-tetradecahydro-3a,6,9,12-tetraaza-cyclopentacyclododecen-5-yl)-hexanoic acid tert-butyl ester 

Relevant articles and documents

A NOVEL DOUBLE DEPROTECTION-PEPTIDE CYCLISATION PROCEDURE AND ITS APPLICATION TO THE SYNTHESIS OF ANALOGUES OF THE CYCLIC TETRAPEPETIDE HC-TOXIN.

A hydroxy-mediated Fmoc/methyl ester double deprotection procedure followed by an improved bis(2-oxo-3-oxazolidinyl)phosphinic chloride (BOP-Cl) cyclisation reaction are reported.This novel methodology was applied to the synthesis of three new HC-toxin analogues.