10487-10-2

Basic information

• Product Name: 2-Pentanone, 5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)-
• Synonyms: 2-Pentanone, 5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)-;1,1,1-Trifluoro-2-hydroxy-2-(trifluoromethyl)pentan-4-one;5,5,5-Trifluoro-4-hydroxy-4-(trifluoromethyl)-2-pentanone;5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)pentan-2-one;1,1,1-Trifluoro-2-trifluoromethyl-2-hydroxy pentan-4-one
• CAS NO: 10487-10-2
• Molecular Formula: C₆H₆F₆O₂
• Molecular Weight: 224.1010592
• Mol File: 10487-10-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 195℃
• Flash Point: 71℃
• Appearance: /
• Density: 1.445
• Vapor Pressure: 0.043mmHg at 25°C
• Refractive Index: 1.3430
• CAS DataBase Reference: 2-Pentanone, 5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentanone, 5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)-(10487-10-2)
• EPA Substance Registry System: 2-Pentanone, 5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)-(10487-10-2)

Safety Data

• Hazardous Substances Data: 10487-10-2(Hazardous Substances Data)

Usage

Description

2-Pentanone, 5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)-, also known as trifluoroacetoin, is a chemical compound with the molecular formula C6H7F6O. It is a trifluorinated derivative of 2-pentanone, which features a unique structure and properties that make it useful in various applications.

Uses

Used in Organic Synthesis:
2-Pentanone, 5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)is used as a solvent in organic synthesis for its ability to dissolve a wide range of organic compounds and facilitate various chemical reactions.
Used in Pharmaceutical and Chemical Research:
2-Pentanone, 5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)is utilized as a reagent in pharmaceutical and chemical research due to its unique structure and properties, which can aid in the development and synthesis of new compounds.
Used in Flavors and Fragrances Industry:
2-Pentanone, 5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)is used as a building block in the production of flavors and fragrances, contributing to the creation of unique scents and tastes.
Used in Pharmaceutical Drug Synthesis:
It is employed in the synthesis of pharmaceutical drugs, where its trifluorinated structure can enhance the properties of the resulting drug molecules, potentially improving their efficacy and pharmacokinetics.
Used in Agrochemicals Synthesis:
2-Pentanone, 5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)is also used in the synthesis of agrochemicals, where its unique properties can contribute to the development of more effective and targeted pesticides or other agricultural products.
Used in New Materials Development:
2-Pentanone, 5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)has potential applications in the development of new materials, where its organofluorine content can impart specific characteristics to the materials, such as increased stability or reactivity.
Used in Organofluorine Compounds Synthesis:
2-Pentanone, 5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)serves as a building block for the synthesis of other organofluorine compounds, which are valuable in various industries due to their unique properties.

InChI:InChI=1/C5H2ClFN2O2/c6-5-4(9(10)11)1-3(7)2-8-5/h1-2H

Upstream product

• 684-16-2 Hexafluoroacetone 
• 67-64-1 acetone 

Downstream Products

• 34844-48-9 1,1,1-trifluoro-2-(trifluoromethyl)pentane-2,4-diol 
• 86350-42-7 Cu((CF₃)2COCH₂C(CH₃)N(C₆H₉(CH₃)(CH(CH₃)2)))2 
• 86350-39-2 Cu((CF₃)2COCH₂C(CH₃)N(CH₂C₆H₅))2 
• 86350-38-1 Cu((CF₃)2COCH₂C(CH₃)N(C₆H₁₁))2 
• 1108201-91-7 TiCl(OCH(CH₃)2)((CF₃)2C(O)CH₂COCH₃)2 
• 86350-41-6 Cu((CF₃)2COCH₂C(CH₃)N(CH(CH₃)(C₆H₅)))2 

Relevant articles and documents

Aluminum, indium, and mixed yttrium-lithium complexes supported by a chiral binap-based fluorinated dialkoxide: Structural features and heteroselective ROP of lactide

The new chiral Binap-based fluorinated dialcohol proteo-ligand {ONNO}H2 has been prepared under its enantiomerically pure and racemic forms following reaction of (R)- or (rac)-1,1′-binaphthyl-2,2′-diamine with 5,5,5-trifluoro-4-hydroxy-4-(trifluoromethyl)pentan-2-one. The racemic proteo-ligand reacts with the trivalent metallic precursors AlEt2Cl and In(CH2SiMe3)3 to yield the complexes (rac)-{ONNO}AlCl (1) and (rac)-{ONNO}In(CH2SiMe3) (2), while the reaction of (R)-{ONNO}H2 with a 1:1 mixture of Y(N(SiMe3)2)3 and LiN(SiMe3)2 gives the enantiomerically pure heterobimetallic [((R)-{ONNO})2Y·Li] (3). Complex 3 acts as a single-component initiator for the near-perfect heteroselective ring-opening polymerization (ROP) of racemic lactide, yielding polymers with Pr up to 0.99 under mild conditions. It also produces syndiotactic-enriched polylactide (Pr = 0.80) by ROP of meso lactide.

Convenient synthesis of mono- and di-β-hydroxy-β-bis(trifluoromethyl)-(di)imines from β-hydroxy-β-bis(trifluoromethyl)-ketones and (di)amines

A series of novel β-hydroxy-β-bis(trifluoromethyl)-imines (2a-j) and di(β-hydroxy-β-bis(trifluoromethyl))-diimines (3a-f) were prepared in moderate to good yields via a simple two-step approach: first, β-hydroxy-β-bis(trifluoromethyl)-ketones (1a-c) were

Fluorinated alkoxy-imino catalyst components

This invention relates to fluorinated alkoxy-imino metallic complexes and their use in catalyst systems for the polymerisation or oligomerisation of ethylene and alpha-olefins.