1048973-47-2 Usage
Description
MDA 19 is a synthetic cannabinoid compound that selectively acts as an agonist for the human peripheral cannabinoid (CB2) receptor. It has been found to have potential therapeutic applications, particularly in the management of neuropathic pain. With reported Ki values of 16.3 nM for human CB2 and 1130 nM for CB1 receptors, MDA 19 demonstrates a high degree of selectivity for the CB2 receptor.
Uses
Used in Pharmaceutical Industry:
MDA 19 is used as a therapeutic agent for the treatment of neuropathic pain. Its agonistic action on the CB2 receptor has been shown to effectively attenuate tactile allodynia in neuropathic rats, suggesting its potential for alleviating neuropathic pain without producing adverse effects in the central nervous system.
Used in Research Applications:
In addition to its potential therapeutic use, MDA 19 is also utilized as a research tool for studying the role of the CB2 receptor in various physiological and pathological processes. Its selectivity for the CB2 receptor makes it a valuable compound for investigating the specific functions and mechanisms of this receptor in different experimental models.
Used in Synthetic Cannabinoid Development:
MDA 19 is an important compound in the development of synthetic cannabinoids, which are designed to mimic the effects of naturally occurring cannabinoids found in the cannabis plant. Its unique properties and selectivity for the CB2 receptor make it a promising candidate for the development of novel therapeutic agents with fewer side effects and improved safety profiles compared to traditional cannabinoids.
Check Digit Verification of cas no
The CAS Registry Mumber 1048973-47-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,4,8,9,7 and 3 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1048973-47:
(9*1)+(8*0)+(7*4)+(6*8)+(5*9)+(4*7)+(3*3)+(2*4)+(1*7)=182
182 % 10 = 2
So 1048973-47-2 is a valid CAS Registry Number.
1048973-47-2Relevant articles and documents
HYDRAZONE MODULATORS OF CANNABINOID RECEPTORS
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Page/Page column 55-56, (2009/03/07)
Hydrazone compounds which modulate cannabinoid receptors are presented. Pharmaceutical compositions containing these compounds, methods of using these compounds as modulators of cannabinoid receptors and processes for synthesizing these compounds are also described herein.
