1062605-69-9 Usage
Description
D,L-O-DESMETHYLVENLAFAXINE-D6, also known as desvenlafaxine-d6, is a deuterated metabolite of Venlafaxine, a selective serotonin noradrenaline reuptake inhibitor (SNRI). It is a white to off-white solid and is used as an internal standard for quantitation of O-desmethylvenlafaxine levels in various applications. D,L-O-DESMETHYLVENLAFAXINE-D6 is characterized by its chemical properties and is a promising pharmaceutical candidate for the treatment of depression and other related disorders.
Uses
1. Used in Antidepressant Applications:
D,L-O-DESMETHYLVENLAFAXINE-D6 is used as an antidepressant for the treatment of major depressive disorder, generalized anxiety disorder, and other anxiety disorders associated with depression. It functions as a selective serotonin noradrenaline reuptake inhibitor, modulating the levels of serotonin and noradrenaline in the brain to alleviate symptoms of depression and anxiety.
2. Used in Clinical Toxicology and Urine Drug Testing:
D,L-O-DESMETHYLVENLAFAXINE-D6 is used as an internal standard for quantitation of O-desmethylvenlafaxine levels in urine or isotope dilution methods by LC/MS or GC/MS. This application is crucial for clinical toxicology, urine drug testing, and forensic analysis, ensuring accurate and reliable measurements of the metabolite in various samples.
3. Used in Forensic Analysis:
In the field of forensic analysis, D,L-O-DESMETHYLVENLAFAXINE-D6 is employed as an internal standard to aid in the identification and quantification of O-desmethylvenlafaxine in biological samples. This helps in determining the presence and concentration of the metabolite, which can be crucial in cases involving the use of antidepressants or other related substances.
4. Used in Pharmaceutical Research and Development:
D,L-O-DESMETHYLVENLAFAXINE-D6 serves as a valuable reference compound in the research and development of new pharmaceuticals targeting depression and anxiety disorders. Its deuterated nature allows for the investigation of its metabolic pathways and potential interactions with other compounds, contributing to the advancement of drug discovery and development in this therapeutic area.
Check Digit Verification of cas no
The CAS Registry Mumber 1062605-69-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,2,6,0 and 5 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1062605-69:
(9*1)+(8*0)+(7*6)+(6*2)+(5*6)+(4*0)+(3*5)+(2*6)+(1*9)=129
129 % 10 = 9
So 1062605-69-9 is a valid CAS Registry Number.
1062605-69-9Relevant articles and documents
SUBSTITUTED PHENETHYLAMINES WITH SEROTONINERGIC AND/OR NOREPINEPHRINERGIC ACTIVITY
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Page/Page column 45, (2008/12/08)
Chemical syntheses and medical uses of novel inhibitors of the uptake of monoamine neurotransmitters and pharmaceutically acceptable salts and prodrugs thereof, for the treatment and/or management of psychotropic disorders, anxiety disorder, generalized a
