1071160-12-7

Basic information

• Product Name: C₃₂H₅₃N₃O₄S
• CAS NO: 1071160-12-7
• Molecular Weight: 575.857
• Mol File: 1071160-12-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₂H₅₃N₃O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₂H₅₃N₃O₄S(1071160-12-7)
• EPA Substance Registry System: C₃₂H₅₃N₃O₄S(1071160-12-7)

Safety Data

• Hazardous Substances Data: 1071160-12-7(Hazardous Substances Data)

Upstream product

• 849052-66-0 (2RS,4R)-2-(4-acetylaminophenyl)-thiazolidine-4-carboxylic acid 
• 122-85-0 para-acetamidobenzaldehyde 
• 948052-48-0 C₁₇H₂₂N₂O₅S 
• 2570-26-5 1-pentadecylamine 

Relevant articles and documents

Synthesis and antiproliferative activity of thiazolidine analogs for melanoma

We have previously described 2-aryl-thiazolidine-4-carboxylic acid amides as a novel class of antiproliferative agents for prostate cancer. Screening these compounds with melanoma cell lines revealed that several of them have potent antiproliferative activity and selectivity against melanoma. To further improve the potency and selectivity, we synthesized a new series of analogs and tested them in two melanoma cell lines and fibroblast cells (negative controls). Comparison of anticancer effects of these compounds with a standard chemotherapeutic agent, sorafenib, showed that they are very effective in killing melanoma cells with low micromolar to nanomolar antiproliferative activity and provide us a new lead for developing potential drugs for melanoma.