1071526-57-2Relevant articles and documents
Potent, orally bioavailable, liver-selective stearoyl-CoA desaturase (SCD) inhibitors
Koltun, Dmitry O.,Zilbershtein, Timur M.,Migulin, Vasily A.,Vasilevich, Natalya I.,Parkhill, Eric Q.,Glushkov, Andrei I.,McGregor, Malcolm J.,Brunn, Sandra A.,Chu, Nancy,Hao, Jia,Mollova, Nevena,Leung, Kwan,Chisholm, Jeffrey W.,Zablocki, Jeff
scheme or table, p. 4070 - 4074 (2010/03/25)
Two structurally distinct series of SCD (Δ9 desaturase) inhibitors (1 and 2) have been previously reported by our group. In the present work, we merged the structural features of the two series. This led to the discovery of compound 5b (CVT-12,012) which
