107207-23-8Relevant articles and documents
Highly stereocontrolled total synthesis of the polyether antibiotic salinomycin. IV. Chemical degradation of salinomycin for the structure confirmation of synthetic key intermediates
Horita,Nagato,Oikawa,Yonemitsu
, p. 1726 - 1730 (2007/10/02)
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A highly stereocontrolled total synthesis of the polyether antibiotic salinomycin. Crucial role of the 4-methoxybenzyl (MPM) protecting group for hydroxy functions
Horita,Oikawa,Nagato,Yonemitsu
, p. 5143 - 5146 (2007/10/02)
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ON THE SELECTIVITY OF DEPROTECTION OF BENZYL, MPM (4-METHOXYBENZYL)AND DMPM (3,4-DIMETHOXYBENZYL) PROTECTING GROUPS FOR HYDROXY FUNCTIONS
Horita, Kiyoshi,Yoshikoa, Tadao,Tanaka, Tatsuyoshi,Oikawa, Yuji,Yonemitsu, Osamu
, p. 3021 - 3028 (2007/10/02)
The 4-methoxybenzyl (MPM) protecting group for hydroxy functions is readily removed with DDQ in dichloromethane containing a small amount of water at room temperature.Under these neutral conditions, several other protecting and functional groups remained unchanged. 3,4-Dimethoxybenzyl (DMPM groups are more reactive than MPM groups with DDQ.The benzyl (Bn) protecting group was removed by catalitic hydrogenation over Raney nickel.Selective deprotection of DMPM, MPM and Bn groups is also presented.