107356-10-5

Basic information

• Product Name: Benzaldehyde, 3-chloro-4-hydroxy-5-methyl-
• CAS NO: 107356-10-5
• Molecular Formula: C8H7ClO2
• Molecular Weight: 170.595
• Mol File: 107356-10-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzaldehyde, 3-chloro-4-hydroxy-5-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzaldehyde, 3-chloro-4-hydroxy-5-methyl-(107356-10-5)
• EPA Substance Registry System: Benzaldehyde, 3-chloro-4-hydroxy-5-methyl-(107356-10-5)

Safety Data

• Hazardous Substances Data: 107356-10-5(Hazardous Substances Data)

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 87-64-9 2-chloro-6-methylphenol 
• 100-97-0 hexamethylenetetramine 

Downstream Products

• 107356-11-6 3-Chloro-5-methyl-4-<<5-(3-methyl-5-isoxazolyl)pentyl>oxy>benzaldehyde 
• 107356-09-2 3-Chloro-5-methyl-4-<<5-(3-methyl-5-isoxazolyl)pentyl>oxy>benzoic acid 
• 118276-20-3 3-Chloro-5-methyl-4-[5-(3-methyl-isoxazol-5-yl)-pentyloxy]-benzoyl chloride 
• 107356-12-7 3-Chloro-N-(2-chloroethyl)-5-methyl-4-<<5-(3-methyl-5-isoxazolyl)pentyl>oxy>benzamide 
• 910575-76-7 (S)-2-(3-chloro-4-hydroxy-5-methyl-benzyl)-4-oxo-4-[4-(2-oxo-1,2,4,5-tetrahydro-benzo[d][1,3]diazepin-3-yl)-piperidin-1-yl]-butanoic acid methyl ester 
• 910575-75-6 (S)-2-(3-chloro-4-hydroxy-5-methyl-benzyl)-succinic acid 1-methyl ester 
• 1262414-37-8 4-[5-(2-cyclopentyl-6-methoxypyridin-4-yl)-[1,3,4]oxadiazol-2-yl]-2-ethyl-6-methylphenol 
• 1262414-36-7 4-[5-(4-benzyloxy-3-ethyl-5-methylphenyl)-[1,3,4]oxadiazol-2-yl]-2-cyclopentyl-6-methoxypyridine 
• 1262414-29-8 4-[3-(2-cyclopentyl-6-methoxypyridin-4-yl)-[1,2,4]oxadiazol-5-yl]-2-ethyl-6-methylphenol 
• 1262414-28-7 4-[5-(4-benzyloxy-3-ethyl-5-methylphenyl)-[1,2,4]oxadiazol-3-yl]-2-cyclopentyl-6-methoxypyridine 
• 944327-05-3 4-benzyloxy-3-ethyl-5-methylbenzoic acid 
• 944327-07-5 4-benzyloxy-3-ethyl-5-methylbenzaldehyde 
• 910814-26-5 3-(3-chloro-4-hydroxy-5-methyl-phenyl)-1-((1aS,5aR)-1,1,2-trimethyl-1,1a,5,5a-tetrahydro-3-thia-cyclopropa[a]pentalen-4-yl)-propenone 
• 910575-74-5 2-[1-(3-chloro-4-hydroxy-5-methyl-phenyl)-meth-(Z)-ylidene]-succinic acid 1-methyl ester 

Relevant articles and documents

SUBSTITUTED PROPANAMIDES AS INHIBITORS OF NUCLEASES

The invention provides compounds represented by the structural formula (1): wherein R1, R2, R3, R4, R5, R6 are as defined in the claims. The compounds are inhibitors of nucleases, and are useful in particular in a method of treatment and/or prevention of proliferative diseases, neurodegenerative diseases, and other genomic instability associated diseases.

NOVEL THIOPHENE DERIVATIVES AS S1P1/EDG1 RECEPTOR AGONISTS

The invention relates to thiophene derivatives of formula (I) / their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunosuppressive agents wherein: A represents *-CO-CH=CH-, *-CO-CH2CH2-, *-CO-CH2-NH-, wherein the sterisks indicate the bond that is linked to the thiophene group of Formula (I) , and R1-R3 are as defined in the claims.

Dehydroamino acids

Compounds of formula 1 and 1-1, wherein R1 is hydrogen, hydroxy, amino or halogen, R2 is hydrogen, hydroxy, or halogen and R3 is hydrogen (Formula 1) or R1 is hydrogen and R2 and R3 taken together with the ethenylene group connecting them form phenyl, pyrrole, pyrroline, oxopyrroline, pyrazole, triazole, or imidazole (Formula 1-1), A is R4 R5 are hydrogen, methyl, ethyl or halogen except that R4 r5 cannot both be hydrogen; and 1) B is hydrogen, or lower alkyl; or 2) B is where R6 R7 R8 and R9 are independently hydrogen, hydroxy, aminosulfonyl, halogen, lower alkoxy, cyano, amino, lower alkyl, lower alkyl amino, or nitro; or 3) B is where R10 is hydrogen, hydroxy, halogen, or lower alkyl and C is a five- or six- membered ring with 0 to 3 heteroatoms which heteroatoms are selected from nitrogen, oxygen, and sulfur, which ring may be unsubstituted or mono- or di- substituted with lower alkyl, cycloalkyl, amino, or substituted amino; 4) B is where X and Y are independently methylene or nitrogen; or 5) B is where at leat one of T, U, V, or W is nitrogen, and any of T, U, V or W which is carbon may be substituted with lower alkyl, lower alkyl amino, lower alkoxy, hydroxy, aminosulfonyl, halogen, cyano, amino, or nitro; or 6) B is where Y is carbon or nitrogen; or 7) B is a five-membered aromatic ring with 1 to 3 heteratoms selected from nitrogen, oxygen, and sulfur which ring may be unsubstituted or mono- or di-substituted with lower alkyl, cycloalky, trifluoroloweralkyl, amino, halogen, substituted amino, or which ring may be fused with a 5 or 6 membered aromatic ring containing 0 to 3 heteroatoms which heteroatoms are selected from nitrogen, oxygen, and sulfur; and pharmaceutically acceptable salts thereof, and related prodrugs, pharmaceutical compositions and methods of treatment, which compounds are useful for treating psoriasis.