107474-65-7

Basic information

• Product Name: methyl pyrrolo<3,2-e>indole-2-carboxylate
• Synonyms: methyl pyrrolo<3,2-e>indole-2-carboxylate
• CAS NO: 107474-65-7
• Molecular Weight: 214.224
• Mol File: 107474-65-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl pyrrolo<3,2-e>indole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl pyrrolo<3,2-e>indole-2-carboxylate(107474-65-7)
• EPA Substance Registry System: methyl pyrrolo<3,2-e>indole-2-carboxylate(107474-65-7)

Safety Data

• Hazardous Substances Data: 107474-65-7(Hazardous Substances Data)

Usage

General Description

Methyl pyrrolo<3,2-e>indole-2-carboxylate is a chemical compound with the molecular formula C14H12N2O2. It is a derivative of pyrroloindole, a heterocyclic compound that contains both a pyrrole and an indole ring. Methyl pyrrolo<3,2-e>indole-2-carboxylate is used in organic synthesis and pharmaceutical research, and it has potential applications in drug development. methyl pyrrolo<3,2-e>indole-2-carboxylate may have diverse biological activities and has been studied for its potential role in cancer treatment, anti-inflammatory properties, and neurological effects. It is important for researchers and scientists to continue exploring the properties and potential uses of methyl pyrrolo<3,2-e>indole-2-carboxylate in various fields of science and medicine.

Upstream product

• 107474-64-6 methyl 2-azido-3-(1H-indol-4-yl)acrylate 
• 1074-86-8 4-formyl indole 
• 1037796-08-9 C₁₂H₁₀N₄O₂ 

Downstream Products

• 1049812-57-8 C₂HF₃O₂*C₅₃H₅₇ClN₁₀O₉ 
• 1049812-54-5 C₄₃H₄₆ClN₉O₆ 
• 107474-66-8 methyl 3-(tert-butyloxycarbonyl)-1,2-dihydro-3H-pyrrolo<3,2-e>indole-7-carboxylate 
• 105518-47-6 3-carbamoyl-1,2-dihydro-3H-pyrrolo[3,2-e]indole-7-carboxylic acid 
• 107474-63-5 methyl 1,2-dihydro-3H-pyrrolo<3,2-e>indole-7-carboxylate 

Relevant articles and documents

CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF

The present disclosure provides drug-ligand conjugates and drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.

Studies on the Total Synthesis of CC-1065: Preparation of a Synthetic, Simplified 3-Carbamoyl-1,2-dihydro-3H-pyrroloindole Dimer/Trimer/Tetramer (CDPI Dimer/Trimer/Tetramer) and Development of Methodolodgy for PDE-I Dimer Methyl Ester Formation

Two synthetic preparations of 3-carbamaoyl-1,2-dihydro-3H-pyrroloindole-7-carboxylic acid (2b, CDPI) and the investigation and development of methodology for the preparation of 3-carbamoyl-1,2-dihydro-3H-pyrroloindole dimer 3 (CDPI dimer) constituting the simplified and stable PDE-I dimer skeleton possessing the B-DNA minor groove complementary shape of the natural product CC-1065 are detailed.The extension of this methodology to the preparation of 3-carbamoyl-1,2-dihydro-3H-pyrroloindole trimer 4 and tetramer 5 (CDPI trimer and tetramer) are described and constitute synthetic, potentially selective, high affinity, noncovalent B-DNA minor groove binding agents.