108283-89-2

Basic information

• Product Name: pyrimethamine
• CAS NO: 108283-89-2
• Molecular Weight: 248.715
• Mol File: 108283-89-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: pyrimethamine(CAS DataBase Reference)
• NIST Chemistry Reference: pyrimethamine(108283-89-2)
• EPA Substance Registry System: pyrimethamine(108283-89-2)

Safety Data

• Hazardous Substances Data: 108283-89-2(Hazardous Substances Data)

Upstream product

• 106-47-8 4-chloro-aniline 
• 108260-15-7 2-(iodomethyl)-6-methyl-4-pyrimidinylamine 
• 461-98-3 4-amino-2,6-dimethylpyrimidine 

Relevant articles and documents

Studies on the Iodination of 4-Amino-2,6-dimethylpyrimidine - A Possibility of the Regiospecific Functionalization

The iodination of 4-amino-2,6-dimethyl-pyrimidine 1a with I2/H2SO4/H2O/H2O2 does not give, as supposed hitherto, the 5-iodo derivative (2) but affords the corresponding 2-iodomethyl derivative 3a.The reaction pathway of the iodination is discussed.The reaction of 3a with nucleophiles leads to a variety of side chain-substituted pyrimidines 5a-j.