108303-76-0

Basic information

• Product Name: 4-Methyl-2-oxo-7-(4-trifluoromethyl-phenyl)-2,3,6,7-tetrahydro-1H-[1,3]diazepine-5-carboxylic acid ethyl ester
• CAS NO: 108303-76-0
• Molecular Weight: 342.318
• Mol File: 108303-76-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Methyl-2-oxo-7-(4-trifluoromethyl-phenyl)-2,3,6,7-tetrahydro-1H-[1,3]diazepine-5-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methyl-2-oxo-7-(4-trifluoromethyl-phenyl)-2,3,6,7-tetrahydro-1H-[1,3]diazepine-5-carboxylic acid ethyl ester(108303-76-0)
• EPA Substance Registry System: 4-Methyl-2-oxo-7-(4-trifluoromethyl-phenyl)-2,3,6,7-tetrahydro-1H-[1,3]diazepine-5-carboxylic acid ethyl ester(108303-76-0)

Safety Data

• Hazardous Substances Data: 108303-76-0(Hazardous Substances Data)

Upstream product

• 402-51-7 4-(trifluoromethyl)phenylmagnesium bromide 
• 54449-02-4 ethyl 4-chloromethyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 

Relevant articles and documents

Preparation of 7-Alkyl-2,3,6,7-tetrahydro-4-alkyl-2-oxo-1H-1,3-diazepine-5-carboxylates by Ring Expansion-Nucleophilic Addition

The preparation of ethyl 7-alkyl-2,3,6,7-tetrahydro-4-alkyl-2-oxo-1H-1,3-diazepine-5-carboxylates 2 by a one pot ring expansion-nucleophilic addition of ethyl 4-chloromethyl-1,2,3,4-tetrahydro-6-alkyl-2-oxopyrimidine-5-carboxylates 1 is described.