108447-55-8Relevant articles and documents
The catalytic decarboxylative allylation of enol carbonates: The synthesis of enantioenriched 3-allyl-3′-aryl 2-oxindoles and the core structure of azonazine
Babu, K. Naresh,Bisai, Alakesh,Khatua, Arindam,Pal, Souvik,Roy, Avishek
supporting information, p. 127 - 131 (2021/12/29)
The catalytic asymmetric synthesis of 3-allyl-3′-aryl 2-oxindoles has been shownviathe Pd(0)-catalyzed decarboxylative allylation of allylenol carbonates. This methodology provides access to a variety of 2-oxindole substrates (5a-v) with all-carbon quater
Palladium-catalyzed asymmetric allylation of prochiral nucleophiles: Synthesis of 3-allyl-3-aryl oxindoles
Trost, Barry M.,Frederiksen, Mathias U.
, p. 308 - 310 (2007/10/03)
Excellent yields and enantioselectivies are attained in the synthesis of 3-alkyl-3-aryl oxindoles based on the Pd-catalyzed asymmetric allylic alkylation (AAA) reaction. This approach utilizes a nonbasic hydroxylic additive in the transformation of 3-aryl
Alkoxyphenylindolinone derivatives, medicaments containing them and their use
-
, (2008/06/13)
Calcium antagonists of the formula STR1 with R(1), R(2), R(3) and R(4) being, inter alia, H, alkyl, alkoxy, halogen, in some cases phenyl; m being 1-4; n being 0-3; X being CH2, O, S, CO, CHOH or CR2, and R(5) being various groups containing nitrogen atoms, are described. They are obtained by reaction of compounds II which are likewise new and which contain in place of R(5) a leaving group Y (Cl, Br, I) with the appropriate (cyclic) amino compound. Another synthesis comprises reaction of the appropriate indolinone derivative IV which has a non-etherified hydroxyl group with a side chain which contains a terminal leaving group Z (Cl, Br, I) in the presence of a base. Furthermore, indolinone derivatives VI with an ether side chain with a terminal epoxide group can be reacted with (cyclic) amines to give compounds I.
