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1088699-54-0

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1088699-54-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1088699-54-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,8,6,9 and 9 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1088699-54:
(9*1)+(8*0)+(7*8)+(6*8)+(5*6)+(4*9)+(3*9)+(2*5)+(1*4)=220
220 % 10 = 0
So 1088699-54-0 is a valid CAS Registry Number.

1088699-54-0Downstream Products

1088699-54-0Relevant articles and documents

Exploring amino acids derivatives as potent, selective, and direct agonists of sphingosine-1-phosphate receptor subtype-1

Evindar, Ghotas,Deng, Hongfeng,Bernier, Sylvie G.,Doyle, Elisabeth,Lorusso, Jeanine,Morgan, Barry A.,Westlin, William F.

, p. 472 - 475 (2013/02/23)

In the quest to discover a potent and selective class of direct agonists to the sphingosine-1-phosphate receptor, we explored the carboxylate functional group as a replacement to previously reported lead phosphates. This has led to the discovery of potent and selective direct agonists with moderate to substantial in vivo lymphopenia. The previously reported selectivity enhancing moiety (SEM) and selectivity enhancing orientation (SEO) in the phenylamide and phenylimidazole scaffolds were crucial to obtaining selectivity for S1P receptor subtype 1 over 3.

HETEROARYL SUBSTITUTED THIAZOLES

-

, (2009/01/20)

The invention provides heteroaryl substituted thiazolo compounds of Formula I and II and pharmaceutically acceptable salts thereof. The variables A and R3 to R7 are defined herein. The invention also includes methods for preparing compounds and salts of Formula I and II. The present invention also includes pharmaceutical compositions containing heteroaryl substituted thiazolo compounds and methods for using heteroaryl substituted thiazolo compounds, including methods for using the compounds in the treatment of hepatitis C virus.

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