108915-10-2

Basic information

• Product Name: (4S,5R)-(+)-4-Methyl-5-phenyl-2-(2-pyridinyl)-2-oxazolin
• Synonyms: (4S,5R)-(+)-4-Methyl-5-phenyl-2-(2-pyridinyl)-2-oxazolin
• CAS NO: 108915-10-2
• Molecular Weight: 238.289
• Mol File: 108915-10-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4S,5R)-(+)-4-Methyl-5-phenyl-2-(2-pyridinyl)-2-oxazolin(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5R)-(+)-4-Methyl-5-phenyl-2-(2-pyridinyl)-2-oxazolin(108915-10-2)
• EPA Substance Registry System: (4S,5R)-(+)-4-Methyl-5-phenyl-2-(2-pyridinyl)-2-oxazolin(108915-10-2)

Safety Data

• Hazardous Substances Data: 108915-10-2(Hazardous Substances Data)

Upstream product

• 492-41-1 (1R,2S)-norephedrine 
• 19547-38-7 methyl pyridine-2-imidate 
• 100-70-9 2-Cyanopyridine 

Relevant articles and documents

Synthesis of Optically Active Bis(2-oxazolines): Crystal Structure of a 1,2-Bis(2-oxazolinyl)benzene * ZnCl2 Complex

Dinitriles (5-7, 12, 13) react with enantiomerically pure β-amino alcohols (8-11, 17) under zinc chloride catalysis to give optically active C2-symmetric bis(oxazolines). 1,2-Bis(2-oxazolin-2-yl)benzenes 1a-e are obtained under mild reaction conditions. 1H-NMR spectroscopy indicates the formation of 1:1 complexes 23 of these compounds with ZnCl2.The energy required for a conformational interconversion of zinc dichloride complex 23e was determined by variable-temperature 1H-NMR studies.An X-ray structure analysis was performed with the substituted zinc dichloride complex 23a.