1092975-69-3Relevant articles and documents
Thallium(III) p-tosylate mediated oxidative 2,3-aryl rearrangement: A new useful route to ipriflavone and its analogs
Muthukrishnan,Singh, Om V.
experimental part, p. 3875 - 3883 (2009/04/11)
A new route for the synthesis of ipriflavone, an antiosteoporotic agent, is described that has four steps and 60% yields starting from resacetophenone (2). The key step of the present methodology is thallium(III) p-tosylate mediated oxidative 2,3-aryl rearrangement of flavanone to generate the isoflavone ring system of ipriflavone in a highly efficient manner. Copyright Taylor & Francis Group, LLC.
