109393-95-5

Basic information

• Product Name: 4,4-bis(4-methoxyphenyl)-4-butyrolactone
• Synonyms: 4,4-bis(4-methoxyphenyl)-4-butyrolactone
• CAS NO: 109393-95-5
• Molecular Weight: 298.339
• Mol File: 109393-95-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4,4-bis(4-methoxyphenyl)-4-butyrolactone(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-bis(4-methoxyphenyl)-4-butyrolactone(109393-95-5)
• EPA Substance Registry System: 4,4-bis(4-methoxyphenyl)-4-butyrolactone(109393-95-5)

Safety Data

• Hazardous Substances Data: 109393-95-5(Hazardous Substances Data)

Upstream product

• 75-15-0 carbon disulfide 
• 7446-70-0 aluminium trichloride 
• 100-66-3 methoxybenzene 
• 543-20-4 succinoyl dichloride 
• 109393-92-2 4,4-bis-(4-methoxy-phenyl)-but-3-enoic acid 
• 7664-39-3 hydrogen fluoride 
• 40938-16-7 (4,4'-dimethoxy-benzhydrylidene)-succinic acid 
• 90-96-0 bis(p-methoxyphenyl)methanone 
• 108-30-5 succinic acid anhydride 
• 13139-86-1 4-methoxyphenyl magnesium bromide 

Downstream Products

• 134179-56-9 4-(4-hydroxyphenyl)naphthalene-1,7-diol 

Relevant articles and documents

Electroreductive coupling of aromatic ketones, aldehydes, and aldimines with α,β-unsaturated esters: Synthesis of 5-aryl substituted γ-butyrolactones and lactams

The electroreductive intermolecular coupling of aromatic ketones and aldehydes with α,β-unsaturated esters in the presence of TMSCl gave the adducts as γ-trimethylsiloxy esters. The detrimethylsilylation of the adducts with TBAF afforded 5-aryl substituted γ-butyrolactones. The electroreductive coupling of N-(4-methoxyphenyl)-1-arylmethaneimines with methyl acrylate in the presence of TMSCl gave the adducts as methyl 4-aryl-4-((4-methoxyphenyl)amino)butanoates. The adducts were transformed to 5-aryl-γ-butyrolactams by cyclization with NaH and subsequent oxidation with CAN. (±)-Norcotinine was prepared from nicotinaldehyde by this method. The electroreductive coupling of aromatic ketones and aldimines with acrylonitrile in the presence of TMSCl gave 4-aryl-4-(trimethylsiloxy)butanenitriles and 4-aryl-4-((4-methoxyphenyl)amino)butanenitriles, respectively.

A Novel Friedel-Crafts Reaction: Synthesis of 4-Phenylnaphthalen-1-ols

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