109705-14-8

Basic information

• Product Name: 1-FLUORO-2,4,6-TRIMETHYLPYRIDINIUM TETRAFLUOROBORATE
• Synonyms: N-FLUORO-2,4,6-TRIMETHYLPYRIDINIUM TETRAFLUOROBORATE;1-FLUORO-2,4,6-TRIMETHYLPYRIDINIUM TETRAFLUOROBORATE;1-fluoro-sym-collidinium tetrafluoro-borate;1-FLUORO-2,4,6-TRIMETHYLPYRIDINIUM TETRA -FLUOROBORATE, 95+%;N-Fluoro-2,4,6-trimethylpyridiniumtetrafluoro;N-fluoro-2,4,6-trimethylpyridinium tetrafluoroborate 98%;N-fluoro-2,4,6-trimethylpyridiniumtetrafluoroborate98%;1-Fluoro-2,4,6-trimethylpyridinium Tetrafluoroborate [Fluorinating Reagent]
• CAS NO: 109705-14-8
• Molecular Formula: C8H11BF5N
• Molecular Weight: 226.98
• Product Categories: B (Classes of Boron Compounds);Electrophilic Fluorinating Reagents;Fluorinating Reagents;Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds;Fluorination;Halogenation;Pyridinium Compounds;Synthetic Organic Chemistry;Tetrafluoroborates
• Mol File: 109705-14-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 213-217 °C(lit.)
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: 1759
• Density: g/cm³
• CAS DataBase Reference: 1-FLUORO-2,4,6-TRIMETHYLPYRIDINIUM TETRAFLUOROBORATE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-FLUORO-2,4,6-TRIMETHYLPYRIDINIUM TETRAFLUOROBORATE(109705-14-8)
• EPA Substance Registry System: 1-FLUORO-2,4,6-TRIMETHYLPYRIDINIUM TETRAFLUOROBORATE(109705-14-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: 1759
• WGK Germany: 3
• F: 8-10-21
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 109705-14-8(Hazardous Substances Data)

Usage

Description

1-FLUORO-2,4,6-TRIMETHYLPYRIDINIUM TETRAFLUOROBORATE is a chemical compound that serves as a versatile reagent in various organic synthesis processes. It is characterized by its unique structure, which includes a fluorine atom and a tetrafluoroborate anion, making it a valuable component in the synthesis of complex organic molecules.

Uses

Used in Organic Synthesis:
1-FLUORO-2,4,6-TRIMETHYLPYRIDINIUM TETRAFLUOROBORATE is used as a reactant for Pd(II)-catalyzed para-selective C-H arylation, enabling the selective formation of desired products in the synthesis of complex organic molecules. This selective arylation is crucial for the development of pharmaceuticals and other specialty chemicals.
Used in Fluorination Reactions:
1-FLUORO-2,4,6-TRIMETHYLPYRIDINIUM TETRAFLUOROBORATE is also used as a reagent in fluorination reactions, where it can introduce a fluorine atom into organic molecules. Fluorination is an important process in the synthesis of various pharmaceuticals, agrochemicals, and materials, as the introduction of fluorine can significantly alter the properties and reactivity of the molecule.
Used in Aryl Trifluoromethylation Reactions:
1-FLUORO-2,4,6-TRIMETHYLPYRIDINIUM TETRAFLUOROBORATE is utilized in aryl trifluoromethylation reactions, which involve the introduction of a trifluoromethyl group (CF3) into aromatic compounds. This modification can enhance the stability, lipophilicity, and biological activity of the resulting molecules, making it an essential process in the development of new drugs and materials.

InChI:InChI=1/C8H11FN.BF4/c1-6-4-7(2)10(9)8(3)5-6;2-1(3,4)5/h4-5H,1-3H3;/q+1;-1