1098072-98-0

Basic information

• Product Name: 5-[1-(2-ethylphenyl)-1-methylethyl]-2,2-dimethyl-1,3-dioxane-4,6-dione
• Synonyms: 5-[1-(2-ethylphenyl)-1-methylethyl]-2,2-dimethyl-1,3-dioxane-4,6-dione
• CAS NO: 1098072-98-0
• Molecular Weight: 290.359
• Mol File: 1098072-98-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-[1-(2-ethylphenyl)-1-methylethyl]-2,2-dimethyl-1,3-dioxane-4,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[1-(2-ethylphenyl)-1-methylethyl]-2,2-dimethyl-1,3-dioxane-4,6-dione(1098072-98-0)
• EPA Substance Registry System: 5-[1-(2-ethylphenyl)-1-methylethyl]-2,2-dimethyl-1,3-dioxane-4,6-dione(1098072-98-0)

Safety Data

• Hazardous Substances Data: 1098072-98-0(Hazardous Substances Data)

Upstream product

• 2231-66-5 2,2-dimethyl-5-(propan-2-ylidene)-1,3-dioxane-4,6-dione 
• 21450-63-5 2-ethylphenylmagnesium bromide 

Downstream Products

• 2033-24-1 cycl-isopropylidene malonate 
• 18970-44-0 1-ethyl-2-isopropylbenzene 
• 3709-18-0 2,2,5-trimethyl-1,3-dioxane-4,6-dione 
• 876405-68-4 5-(4-fluorobenzyl)-2,2-dimethyl-[1,3]dioxane-4,6-dione 
• 132871-86-4 1-(tert-butyl)-2-ethylbenzene 

Relevant articles and documents

Carbon-based leaving group in substitution reactions: Functionalization of sp3-hybridized quaternary and tertiary benzylic carbon centers

Lewis acid promoted substitution reactions employing Meldrum's acid and 5-methyl Meldrum's acid as carbon-based leaving groups are described which transform unstrained quaternary and tertiary benzylic Csp 3-Csp3 bonds into Csp3-X bonds (X = C, H, N). Importantly, this reaction has a broad scope in terms of both suitable substrates and nucleophiles with good to excellent yields obtained (typically >90%).