1099474-28-8 Usage
Description
(4R-cis)-1,1-Dimethylethyl 6-[2[2-(fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate is a complex organic compound with a unique molecular structure. It is characterized by its chiral center at the 4R position and a cis configuration, which gives it specific properties and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
(4R-cis)-1,1-Dimethylethyl 6-[2[2-(fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate is used as an impurity in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. It plays a crucial role in the development and production of Atorvastatin, which is a widely prescribed medication for lowering cholesterol levels and reducing the risk of cardiovascular diseases.
Used in Research and Development:
(4R-cis)-1,1-Dimethylethyl 6-[2[2-(fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate can also be used in research and development for studying its chemical properties, potential interactions with other molecules, and possible applications in various fields. Its unique structure and chiral center make it an interesting subject for scientific investigation and potential development of new drugs or materials.
Check Digit Verification of cas no
The CAS Registry Mumber 1099474-28-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,9,9,4,7 and 4 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1099474-28:
(9*1)+(8*0)+(7*9)+(6*9)+(5*4)+(4*7)+(3*4)+(2*2)+(1*8)=198
198 % 10 = 8
So 1099474-28-8 is a valid CAS Registry Number.
1099474-28-8Relevant articles and documents
Preparation method of atorvastatin calcium isomers
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, (2018/09/11)
The invention relates to a preparation method of atorvastatin calcium isomers [R-(R*,R*)]-2-(3-fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-2-phenyl-4-[(aniline)carbonyl]-1H-pyrrole-1-calciumenanthate salt (IMP-1 for short) and [R-(R*,R*)]-3-(2-fluorophenyl)-beta, delta-dihydroxyl -5-(1-Methylethyl)-3-phenyl-4-[(anilino)carbonyl]-1H-pyrrole-1- calcium enanthate salt (IMP-2 for short). According to the preparation method, a preparation method of a reference substance is provided for the quality research of drugs, and an important guiding significance is provided for the safe medicationof atorvastatin calcium.
