110773-63-2

Basic information

• Product Name: (S)-(+)-2-(2-naphthyl)propanal
• Synonyms: (S)-(+)-2-(2-naphthyl)propanal
• CAS NO: 110773-63-2
• Molecular Weight: 184.238
• Mol File: 110773-63-2.mol
• Article Data: 50

Chemical Properties

• CAS DataBase Reference: (S)-(+)-2-(2-naphthyl)propanal(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-2-(2-naphthyl)propanal(110773-63-2)
• EPA Substance Registry System: (S)-(+)-2-(2-naphthyl)propanal(110773-63-2)

Safety Data

• Hazardous Substances Data: 110773-63-2(Hazardous Substances Data)

Upstream product

• 64481-21-6 2-methyl-2-(naphthalene-2-yl)oxirane 
• 4009-98-7 (methoxymethyl)triphenylphosphonium chloride 
• 93-08-3 methyl 2-naphthyl ketone 
• 201230-82-2 carbon monoxide 
• 827-54-3 2-naphthylethylene 
• 581-96-4 2-naphthylacetic acid 
• 33670-32-5 methoxymethyltriphenylphosphonium bromide 
• 2876-71-3 methyl 2-naphthylacetate 
• 57421-64-4 methyl α-(2-naphthyl)propionate 
• 873932-84-4 2-(naphthalen-2-yl)prop-2-en-1-ol 
• 21567-68-0 1-(naphthalen-2-yl)propan-2-one 
• 854248-80-9 1-(1-methoxyprop-1-en-2-yl)naphthalene 
• 38964-52-2 (±)-2-(naphthalen-2-yl)propan-1-ol 
• 3710-23-4 2-isopropenylnaphthalene 

Downstream Products

• 1342313-23-8 2-methyl-2-(naphthalen-2-yl)-4-(1-phenyl-1H-tetrazol-5-ylsulfonyl)butanal 
• 93-08-3 methyl 2-naphthyl ketone 
• 1220126-40-8 (R)-4-methyl-4-(naphthalen-2-yl)cyclohex-2-enone 
• 1220126-41-9 (+)-2,4-dimethyl-4-(2-naphthyl)-2-cyclohexenone 
• 132278-86-5 Benzyl-methyl-(1-methyl-1-naphthalen-2-yl-prop-2-ynyl)-amine 

Relevant articles and documents

Ligand-metal cooperating PC(sp3)P pincer complexes as catalysts in olefin hydroformylation

Ligand-metal cooperation: A new ligand-metal cooperating catalyst for the hydroformylation of olefins is described (see scheme). The mechanism of the H2 activation and C-H bond formation of the catalyst involves an intramolecular cooperation between the structurally remote functionality and the metal center and proceeds without change of the oxidation state of the metal.

Synthesis of rac-ɑ-aryl propionaldehydes via branched-selective hydroformylation of terminal arylalkenes using water-soluble Rh-PNP catalyst

This work detailed the preparation of a class of water-soluble PNP ligands that differed by the nature of the substitute on phenyl ring of ligands. These ligands were incorporated into water-soluble rhodium-PNP complex catalysts that were used to regioselective hydroformylation of a series of terminal arylalkenes, providing efficient access to rac-α-aryl propionaldehydes in good to excellent yield (up to 97%) and branched-regioselectivity (up to 40:1 b/l ratio). Furthermore, gram-scale and diverse synthetic transformation demonstrated synthetic application of this methodology for non-steroidal antiinflammatory drugs.

Palladium-Catalyzed Allenamide Carbopalladation/Allylation with Active Methine Compounds

A palladium-catalyzed allenamide carbopalladation/allylation with active methine compounds has been developed. Various indoles and isoquinolinones bearing a quaternary carbon center were achieved with good efficiency, a broad substrate scope and good functional group tolerance. This reaction underwent cascade oxidative addition, carbopalladation, and allylic alkylation, and two new C-C bonds were formed in one pot.

Copper-catalyzed hydroformylation and hydroxymethylation of styrenes

Hydroformylation catalyzed by transition metals is one of the most important homogeneously catalyzed reactions in industrial organic chemistry. Millions of tons of aldehydes and related chemicals are produced by this transformation annually. However, most of the applied procedures use rhodium catalysts. In the procedure described here, a copper-catalyzed hydroformylation of alkenes has been realized. Remarkably, by using a different copper precursor, the aldehydes obtained can be further hydrogenated to give the corresponding alcohols under the same conditions, formally named as hydroxymethylation of alkenes. Under pressure of syngas, various aldehydes and alcohols can be produced from alkenes with copper as the only catalyst, in excellent regioselectivity. Additionally, an all-carbon quaternary center containing ethers and formates can be synthesized as well with the addition of unactivated alkyl halides. A possible reaction pathway is proposed based on our results. This journal is