110815-30-0

Basic information

• Product Name: Acetic acid (R)-2-benzyloxycarbonylamino-3-(6-nitro-1H-indol-3-yl)-3-oxo-propyl ester
• Synonyms: Acetic acid (R)-2-benzyloxycarbonylamino-3-(6-nitro-1H-indol-3-yl)-3-oxo-propyl ester
• CAS NO: 110815-30-0
• Molecular Weight: 425.398
• Mol File: 110815-30-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetic acid (R)-2-benzyloxycarbonylamino-3-(6-nitro-1H-indol-3-yl)-3-oxo-propyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (R)-2-benzyloxycarbonylamino-3-(6-nitro-1H-indol-3-yl)-3-oxo-propyl ester(110815-30-0)
• EPA Substance Registry System: Acetic acid (R)-2-benzyloxycarbonylamino-3-(6-nitro-1H-indol-3-yl)-3-oxo-propyl ester(110815-30-0)

Safety Data

• Hazardous Substances Data: 110815-30-0(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 7524-52-9 (S)-tryptophan methyl ester hydrochloride 
• 61535-47-5 benzyl (S)-(1-hydroxy-3-(1H-indol-3-yl)propan-2-yl)carbamate 
• 2717-76-2 (S)-N-benzyloxycarbonyl-L-tryptophan methyl ester 
• 110815-27-5 (S)-(2-acetoxy)-1-((1H-indol-3-ylmethyl)ethyl)carbamic acid, phenylmethyl ester 
• 110815-28-6 (R)-(1-((acetoxy)methyl)-2-(1H-indol-3-yl)-2-oxoethyl)carbamic acid phenylmethyl ester 

Relevant articles and documents

A Regio- and stereocontrolled total synthesis of (-)-indolactam-V

(-)-Indolactam-V (IL-V) (1)-was prepared in 10 steps from L-tryptophan methyl ester in 17.1% overall yield. The key steps involve regiospecific thallation of the acylindole intermediate (4), followed by azide displacement and reduction to introduce the 13-amino group. Control of the C-11 stereocenter was achieved by SN2 displacement of the chiral inflate (10), derived from D-valine. The thallium mediated closure of dipeptide (17) did not provide an alternative route to IL-V.