111047-29-1

Basic information

• Product Name: Acetamide, 2-iodo-N-1,10-phenanthrolin-5-yl-
• Synonyms: 5-Iodoacetamidophenanthroline;2-iodo-N-1,10-phenanthrolin-5-ylacetamide;Acetamide,2-iodo-N-1,10-phenanthrolin-5-yl;5-iodoacetamido-1,10-phenanthroline
• CAS NO: 111047-29-1
• Molecular Formula: C14H10IN3O
• Molecular Weight: 363.15300
• Mol File: 111047-29-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 180 °C (decomp)(Solv: chloroform (67-66-3))
• Boiling Point: 591.5±40.0 °C(Predicted)
• Density: 1.852±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Acetamide, 2-iodo-N-1,10-phenanthrolin-5-yl-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2-iodo-N-1,10-phenanthrolin-5-yl-(111047-29-1)
• EPA Substance Registry System: Acetamide, 2-iodo-N-1,10-phenanthrolin-5-yl-(111047-29-1)

Safety Data

• Hazardous Substances Data: 111047-29-1(Hazardous Substances Data)

Usage

Description

Acetamide, 2-iodo-N-1,10-phenanthrolin-5-ylis a chemical compound that features an acetamide group attached to a 2-iodo-N-1,10-phenanthrolin-5-yl moiety. This unique structure endows it with specific chemical properties and potential applications in various fields.

Uses

Used in Chemical Synthesis Industry:
Acetamide, 2-iodo-N-1,10-phenanthrolin-5-ylis used as a key intermediate in the synthesis of a heterogeneous artificial metallolipase with chimeric catalytic activity. This innovative metallolipase has the potential to catalyze a wide range of chemical reactions, offering new possibilities for the development of efficient and selective catalysts in various chemical processes.

Upstream product

• 4199-88-6 5-Nitro-1,10-phenanthroline 
• 54258-41-2 1,10-phenanthroline-5-amine 
• 54907-61-8 iodoacetic anhydride 

Relevant articles and documents

Synthesis and Characterisation of a New DNA-binding Bifunctional Ruthenium(II) Complex

A new DNA-binding molecule, Ru(tap)2POQ(2+), in which a polypyridylruthenium(II) complex is linked to an aminochloroquinoline by a flexible chain, has been prepared and characterised (tap = 1,4,5,8-tetraazaphenanthrene and POQ corresponds to a 1,10-phenanthroline linked to an aminochloroquinoline by an aliphatic chain).This complex is regarded as bifunctional because it contains two moieties of different binding modes and photoreactivities vs.DNA.The (1)H NMR data of this compound indicate the presence of an equilibrium between two molecular species.The spectroscopic properties of Ru(tap)2POQ(2+) in absorption and luminescence are examined and compared with those of the corresponding ruthenium(II) complex which does not contain the aminochloroquinoline moiety: Ru(tap)2phen(2+).Luminescence relative quantum yields and lifetimes show that the MLCT excited-state behaviour is influenced by the presence of the linked quinoline.An intramolecular photoinduced electron transfer in one of the two species in equilibrium, is considered to be responsible for a quenching of the ruthenium(II) complex luminescence.Preliminary results on the binding characteristics of Ru(tap)2POQ(2+) to DNA and )>2 from luminescence and thermal denaturation studies are reported.The intramolecular quenching of luminescence in Ru(tap)2POQ(2+) is inhibited when it interacts with nucleic acids.Consequently, the resulting emission is more substantially enhanced in the presence of the polynucleotide relative to the luminescence increase observed with the reference complex, Ru(tap)2phen(2+).

ATP- and iron-protein-independent activation of nitrogenase catalysis by light

We report here the light-driven activation of the molybdenum-iron-protein (MoFeP) of nitrogenase for substrate reduction independent of ATP hydrolysis and the iron-protein (FeP), which have been believed to be essential for catalytic turnover. A MoFeP variant labeled on its surface with a Ru-photosensitizer is shown to photocatalytically reduce protons and acetylene, most likely at its active site, FeMoco. The uncoupling of nitrogenase catalysis from ATP hydrolysis should enable the study of redox dynamics within MoFeP and the population of discrete reaction intermediates for structural investigations.