111705-51-2

Basic information

• Product Name: 3-Furanamine, tetrahydro-N-(triphenylmethyl)-, (S)-
• CAS NO: 111705-51-2
• Molecular Formula: C23H23NO
• Molecular Weight: 329.442
• Mol File: 111705-51-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-Furanamine, tetrahydro-N-(triphenylmethyl)-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Furanamine, tetrahydro-N-(triphenylmethyl)-, (S)-(111705-51-2)
• EPA Substance Registry System: 3-Furanamine, tetrahydro-N-(triphenylmethyl)-, (S)-(111705-51-2)

Safety Data

• Hazardous Substances Data: 111705-51-2(Hazardous Substances Data)

Upstream product

• 111705-49-8 [(S)-4-Hydroxy-3-(trityl-amino)-butyl]-dimethyl-sulfonium; iodide 
• 100841-18-7 (S)-(+)-4-Methylthio-2-triphenylmethylamino-1-butanol 

Downstream Products

• 104530-80-5 (S)-(-)-tetrahydro-3-furylamine p-toluenesulfonate salt 

Relevant articles and documents

Diacylglycerol acyltransferase inhibitors

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.

Preparation of Optically Active Cyclic Ether Derivatives of Amino Acids and Peptides

Treatment of N-tritylmethioninol (1) or peptides (6), incorporating methionyl and amino alcohol residues, with MeI, followed by base mediated cyclisation of the thus derived sulphonium salts, provides the title compounds in excellent yields.