1137261-89-2

Basic information

• Product Name: 1-(4-hydroxy-phenyl)-heptane-1,3-dione
• Synonyms: 1-(4-hydroxy-phenyl)-heptane-1,3-dione
• CAS NO: 1137261-89-2
• Molecular Weight: 220.268
• Mol File: 1137261-89-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-(4-hydroxy-phenyl)-heptane-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-hydroxy-phenyl)-heptane-1,3-dione(1137261-89-2)
• EPA Substance Registry System: 1-(4-hydroxy-phenyl)-heptane-1,3-dione(1137261-89-2)

Safety Data

• Hazardous Substances Data: 1137261-89-2(Hazardous Substances Data)

Upstream product

• 539-82-2 ethyl n-valerate 
• 99-93-4 4-Hydroxyacetophenone 
• 1137261-88-1 1-(4-benzyloxyphenyl)-heptane-1,3-dione 
• 624-24-8 methyl valerate 
• 109-92-2 ethyl vinyl ether 

Downstream Products

• 141645-16-1 2-n-butyl-3-(4-hydroxybenzoyl)-5-nitrobenzofuran 
• 1137261-95-0 1-(4-hydroxyphenyl)heptane-1,3-dione-3-[O-(4-nitrophenyl)oxime] 
• 1253293-38-7 1-(4-hydroxy-phenyl)-heptane-1,3-dione 3-[O-(4-nitro-phenyl)-oxime] 

Relevant articles and documents

PROCESS FOR PREPARING 2-ALKYL-3-AROYL-5-NITRO-BENZOFURANS

The present invention relates to a process for the preparation of a compound of formula wherein R1 is selected from C1-6-alkyl, C3-6-cycloalkyl and aralkyl, and wherein R2 at each occurrence independently is halogen or C1-6-alkyl, and m is an integer from 0 to 4, Q is selected from halogen, —NO2 and —NR3R4, wherein R3 and R4 are independently selected from hydrogen, C1-6-alkyl, C3-6-cycloalkyl, aryl, aralkyl, mesyl and tosyl, or wherein R3 and R4 together form a C4-6-alkylene group, Y at each occurrence is hydrogen or a hydroxy protection group W that can be hydrolytically cleaved under acidic conditions, and n is an integer from 1 to 3, and n is an integer from 1 to 3, with the proviso that n and m together are not greater than 5.

PROCESS FOR PREPARING 2-ALKYL-3-AROYL-5-NITRO-BENZOFURANS

The present invention relates to a process for the preparation of a compound of formula (I), wherein R1 is selected from C1-6-alkyl, C3-6-cycloalkyl and aralkyl, and wherein R2 at each occurrence independently is halogen or C1-6-alkyl, and m is an integer from 0 to 4, Q is selected from halogen, -NO2 and -NR3R4, wherein R3 and R4 are independently selected from hydrogen, C1-6-alkyl, C3-6-cycloalkyl, aryl, aralkyl, mesyl and tosyl, or wherein R3 and R4 together form a C4-6-alkylene group, Y at each occurrence is hydrogen or a hydroxy protection group W that can be hydrolytically cleaved under acidic conditions, and n is an integer from 1 to 3, and n is an integer from 1 to 3, with the proviso that n and m together are not greater than 5.

NEW PROCESS FOR PREPARING DIKETONES AND MEDICAMENTS

There is provided a process for the preparation of a compound of formula (III), wherein X and Y are as described in the description. Such compounds may, for example, be useful intermediates in the synthesis of drugs such as Dronedarone. There is also provided a process for the preparation of a compound of formula (I).