113873-76-0Relevant articles and documents
N,N'-disubstituted urea compound and synthesis method thereof
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Paragraph 0058-0061, (2019/04/10)
The invention discloses an N,N'-disubstituted urea compound and a preparation method thereof. N-alkyl acyloxy amide is taken as a raw material and a dichloro(p-cymene)ruthenium(II) dimer complex is taken as a catalyst for carrying out a reaction in an organic solvent under the presence of silver acetate, and the N,N'-disubstituted urea compound is prepared. Compared with the prior art, the methodhas the following advantages that only an amide derivative is taken as a raw material, reaction conditions are mild, the application range of substrates is wide, operation is simple and convenient, the catalyst is low in price, and selectivity of the product is high.