114136-63-9

Basic information

• Product Name: 2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-2-fluorophenyl)-6-(trifluoromethyl)-
• CAS NO: 114136-63-9
• Molecular Formula: C11H5ClF4N2O2
• Molecular Weight: 308.62
• Mol File: 114136-63-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-2-fluorophenyl)-6-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-2-fluorophenyl)-6-(trifluoromethyl)-(114136-63-9)
• EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-2-fluorophenyl)-6-(trifluoromethyl)-(114136-63-9)

Safety Data

• Hazardous Substances Data: 114136-63-9(Hazardous Substances Data)

Usage

General Description

2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-2-fluorophenyl)-6-(trifluoromethyl)- is a chemical compound that contains a pyrimidinedione ring with a 3-(4-chloro-2-fluorophenyl) and 6-(trifluoromethyl) substituent. It is a heterocyclic compound with potential pharmaceutical applications due to its structure and properties. The presence of the chloro and fluoro groups makes this compound potentially useful in medicinal chemistry for the development of new drugs. Its specific properties and potential biological activity could make it valuable for research and development in the pharmaceutical industry.

Upstream product

• 691-77-0 (E)-3-trifluoromethyl-2-butenoic acid ethyl ester 
• 57946-56-2 2-fluoro-4-chloroaniline 
• 541-41-3 chloroformic acid ethyl ester 
• 114108-90-6 ethyl N-(4-chloro-2-fluorophenyl)carbamate 
• 141860-79-9 2-(dimethylamino)-4-(trifluoromethyl)-6H-1,3-oxazine-6-one 
• 372-29-2 ethyl 3-amino-4,4,4-trifluoro-2-butenoate 
• 69922-26-5 2-fluoro-4-chlorophenyl isocyanate 
• 141860-78-8 ethyl 3-amino-4,4,4-trifluorocrotonate 
• 6674-22-2 1,8-diazabicyclo[5.4.0]undec-7-ene 

Downstream Products

• 114136-66-2 1-methyl-6-trifluoromethyl-3-(4-chloro-2-fluorophenyl)-2,4(1H,3H)-pyrimidinedione 
• 114136-76-4 2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]aniline 

Relevant articles and documents

Discovery of N-Phenylaminomethylthioacetylpyrimidine-2,4-diones as Protoporphyrinogen IX Oxidase Inhibitors through a Reaction Intermediate Derivation Approach

Protoporphyrinogen oxidase (PPO, EC 1.3.3.4) is an effective target for green herbicide discovery. In this work, we reported the unexpected discovery of a novel series of N-phenylaminomethylthioacetylpyrimidine-2,4-diones (2-6) as promising PPO inhibitors

Synthesis of Cyclopropyl Ester and Amide Substituted Pyrimidinediones as Protoporphyrinogen Oxidase-Inhibiting Herbicides

The protoporphyrinogen oxidase (PPO) enzyme is involved in the biosynthesis of chlorophyll and is an important target in research for development of new herbicides. In this study, new pyrimidinedione compounds with thioester tail group containing cyclopropyl moiety are synthesized from the commercially available 2-(1-(mercaptomethyl)cyclopropyl)acetic acid. The herbicidal activity of the synthesized compounds is also evaluated. Most of the synthesized compounds exhibit herbicidal activities against both monocot and dicot weeds. In particular, 10a showed similar activity to the control material, Saflufenacil. And when against the monocot weeds, Echinochloa crusgalli and Digitaria sanguinalis, 10a shows superior activity to Saflufenacil.

SUBSTITUTED THIOPHENYL URACILS, SALTS THEREOF AND THE USE THEREOF AS HERBICIDAL AGENTS

The invention relates to substituted thiophenyl uracils of general formula (I) or the salts (I) thereof, wherein the groups in general formula (I) are as defined in the description, and to the use thereof as herbicides, in particular for controlling weeds and/or weed grasses in crops of cultivated plants and/or as plant growth regulators for influencing the growth of crops of cultivated plants.