115134-69-5

Basic information

• Product Name: 3-hydroxy-3-methylthiazolo<1,2-b>indol-9-yltriphenylphosphonium bromide
• Synonyms: 3-hydroxy-3-methylthiazolo<1,2-b>indol-9-yltriphenylphosphonium bromide
• CAS NO: 115134-69-5
• Molecular Weight: 546.467
• Mol File: 115134-69-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-3-methylthiazolo<1,2-b>indol-9-yltriphenylphosphonium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-3-methylthiazolo<1,2-b>indol-9-yltriphenylphosphonium bromide(115134-69-5)
• EPA Substance Registry System: 3-hydroxy-3-methylthiazolo<1,2-b>indol-9-yltriphenylphosphonium bromide(115134-69-5)

Safety Data

• Hazardous Substances Data: 115134-69-5(Hazardous Substances Data)

Upstream product

• 603-35-0 triphenylphosphine 
• 108288-40-0 2-(bromomethyl)phenyl isothiocyanate 
• 115134-61-7 2-isothiocyanatobenzyltriphenylphosphonium bromide 
• 598-31-2 1-bromoacetone 

Downstream Products

• 115134-70-8 2-(2-oxopropyl-1-thio)indolyl-3-triphenylphosphonium bromide 
• 115134-71-9 2-(2-oxopropyl-1-thio)-3-triphenylphosphonium-1-indolate 

Relevant articles and documents

2-ISOTHIOCYANATOBENZYLTRIPHENYLPHOSPHONIUM BROMIDES - NEW TYPE OF FUNCTIONALIZED HETEROCUMULENES SUITABLE FOR SYNTHESIS OF INDOLE DERIVATIVES

Reaction of 2-bromomethylphenyl isothiocyanates with triphenylphosphine afforded triphenyl-(2-isothiocyanatobenzyl)phosphonium salts.Their reaction with bases liberated the corresponding carbanions which on intramolecular addition to the N=C=S group gave substituted 3-triphenylphosphoniumindolyl-2-thiolates.These compounds did not react in the Wittig reaction but underwent electrophilic reactions on the sulfur atom or the indol nitrogen atom.According to a detailed analysis of 1H, 13C, 31P NMR and mass spectra, the indole derivatives exist predominantly in the betaine form.X-Ray diffraction analysis of the unsubstituted betaine, 3-triphenylphosphoniumindolyl-2-thiolate, agrees well with the spectral results.