115724-85-1Relevant articles and documents
DIFFERENT MODES OF ALKALINE HYDROLYSIS OF FERVENULIN AND ISOFERVENULIN
Shorshnev, S. V.,Esipov, S. E.,Chernyshev, A. I.,Pozharskii, A. F.,Nanavyan, I. M.,Kuz'menko, V. V.
, p. 1247 - 1251 (1987)
Unlike rheumycin and fervenulin, isofervenulin and 3-methylisofervenulin are hydrolyzed by aqueous alkalies at the N(5)-C(6) bond.On acidification of the reaction mixture, the N-carboxy-N-methylcarbamoyltriazines formed are reconverted into the starting isofervenulins, and on basification (pH > 10) into methylaminotriazinecarboxamides.A by-product of the alkaline hydrolysis of isofervenulin is a product of the contraction of the uracil ring, namely imidazotriazinone-7a-carboxylic acid.