116082-98-5

Basic information

• Product Name: S-4-nitrophenyl 4-nitrobenzenesulfinothioate
• Synonyms: S-4-nitrophenyl 4-nitrobenzenesulfinothioate
• CAS NO: 116082-98-5
• Molecular Weight: 324.338
• Mol File: 116082-98-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: S-4-nitrophenyl 4-nitrobenzenesulfinothioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-4-nitrophenyl 4-nitrobenzenesulfinothioate(116082-98-5)
• EPA Substance Registry System: S-4-nitrophenyl 4-nitrobenzenesulfinothioate(116082-98-5)

Safety Data

• Hazardous Substances Data: 116082-98-5(Hazardous Substances Data)

Upstream product

• 100-32-3 di(p-nitrophenyl) disulfide 
• 161941-53-3 4,5-Epoxy-2-methyl-2-pentyl 4-nitrobenzenesulfenate 

Relevant articles and documents

Natural product inspired allicin analogs as novel anti-cancer agents

A series of novel analogs of Allicin (S-allyl prop-2-ene-1-sulfinothioate) present in garlic has been synthesized in high yield. Synthesized 23 compounds were evaluated against different breast cancer cells (MDA-MB-468 and MCF-7) and non-cancer cells (WI38). Four compounds (3f, 3h, 3m and 3u) showed significant cytotoxicity against cancer cells whereas nontoxic to the normal cells. Based on the LD50 values and selectivity index (SI), compound 3h (S-p-methoxybenzyl (p-methoxyphenyl)methanesulfinothioate) was considered as most promising anticancer agent amongst the above three compounds. Further bio-chemical studies confirmed that compound 3h promotes ROS generation, changes in mitochondrial permeability transition and induced caspase mediated DNA damage and apoptosis.