116355-18-1

Basic information

• Product Name: 6-Bromo-7-methylimidazo[1,2-a]pyridine
• Synonyms: 6-Bromo-7-methylimidazo[1,2-a]pyridine;6-Bromo-7-methylimidazo[1,2-a]pyridine 98%;6-broMo-7-MethylH-iMidazo[1;6-Bromo-7-methylimidazo[1,2-a]pyridine98%
• CAS NO: 116355-18-1
• Molecular Formula: C₈H₇BrN₂
• Molecular Weight: 211.05858
• Product Categories: blocks;Bromides;Imidazoles;Pyridines
• Mol File: 116355-18-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.607 g/cm³
• Refractive Index: 1.663
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-Bromo-7-methylimidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Bromo-7-methylimidazo[1,2-a]pyridine(116355-18-1)
• EPA Substance Registry System: 6-Bromo-7-methylimidazo[1,2-a]pyridine(116355-18-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 116355-18-1(Hazardous Substances Data)

Usage

General Description

6-Bromo-7-methylimidazo[1,2-a]pyridine is a chemical compound that belongs to the class of imidazo[1,2-a]pyridines, which are heterocyclic aromatic compounds. It is a potent mutagen and is classified as a probable human carcinogen. 6-Bromo-7-methylimidazo[1,2-a]pyridine is often found in cooked meats, particularly in grilled or charred meats, as a result of the Maillard reaction, a chemical reaction between amino acids and reducing sugars. 6-Bromo-7-methylimidazo[1,2-a]pyridine has been studied for its potential health effects, particularly its carcinogenic properties, and has been the focus of research to understand its impact on human health and to develop strategies to mitigate its presence in food products.

InChI:InChI=1/C8H7BrN2/c1-6-4-8-10-2-3-11(8)5-7(6)9/h2-5H,1H3

Upstream product

• 107-20-0 2-chloroethanal 
• 98198-48-2 2-amino-5-bromo-4-methylpyridine 

Downstream Products

• 1464151-75-4 4-(7-methyl-6-(4-(4-methylpiperazine-1-carbonyl)phenyl)imidazo[1,2-a]pyridin-3-yl)benzonitrile 
• 1464151-74-3 4-(6-(4-(4-amino-4-methylpiperidine-1-carbonyl)phenyl)-7-methylimidazo[1,2-a]pyridin-3-yl)benzonitrile 
• 1464156-26-0 tert-butyl 1-(4-(3-(4-cyanophenyl)-7-methylimidazo[1,2-a]pyridin-6-yl)benzoyl)-4-methylpiperidin-4-ylcarbamate 
• 1464156-21-5 4-(3-(4-cyanophenyl)-7-methylimidazo[1,2-a]pyridin-6-yl)benzoic acid 
• 1464156-18-0 ethyl 4-(3-(4-cyanophenyl)-7-methylimidazo[1,2-a]pyridin-6-yl)benzoate 
• 1464156-15-7 4-(6-bromo-7-methylimidazo[1,2-a]pyridin-3-yl)benzonitrile 

Relevant articles and documents

5-AZAINDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS

The present invention relates to novel 5-azaindazole derivatives of formula (I), as described and defined herein, and pharmaceutically acceptable salts, solvates and prodrug thereof, as well as pharmaceutical compositions comprising such compounds. The 5-azaindazole derivatives according to the invention have been found to be highly effective dual A2A/A2B adenosine receptor antagonists, and can thus be used as therapeutic agents, particularly in the treatment or prevention of hyperproliferative or infectious diseases or disorders.

IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF

The invention provides compounds of formula (1), stereoisomers and tautomers thereof, or pharmaceutically acceptable salts, solvates and polymorphs thereof, and processes for their preparation. The invention further relates to pharmaceutical compositions containing said compounds and their use in the treatment of diseases or disorders mediated by one or more proinflammatory cytokines selected from TNF-a, IL-Ιβ, IL-6, IL-8, IL-12, IL-17 or IL-23.

INHIBITORS OF PI3 KINASE

The present invention relates to compounds of Formula I, II or III or a pharmaceutically acceptable salt thereof; methods of treating diseases or conditions, such as cancer, using the compounds; and pharmaceutical compositions containing the compounds, wherein the variables are as defined herein