116672-26-5

Basic information

• Product Name: Methanone, (4-methyl-1-naphthalenyl)phenyl-
• CAS NO: 116672-26-5
• Molecular Formula: C18H14O
• Molecular Weight: 246.309
• Mol File: 116672-26-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Methanone, (4-methyl-1-naphthalenyl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (4-methyl-1-naphthalenyl)phenyl-(116672-26-5)
• EPA Substance Registry System: Methanone, (4-methyl-1-naphthalenyl)phenyl-(116672-26-5)

Safety Data

• Hazardous Substances Data: 116672-26-5(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 90-12-0 1-Methylnaphthalene 
• 71-43-2 benzene 
• 65-85-0 benzoic acid 
• 140-29-4 phenylacetonitrile 
• 86-52-2 1-Chloromethylnaphthalene 
• 33738-48-6 4-methyl-1-naphthaldehyde 
• 98-80-6 phenylboronic acid 
• 121-46-0 bicyclo[2.2.1]hepta-2,5-diene 
• 171258-08-5 2-(phenylethynyl)acetophenone 

Downstream Products

• 109558-90-9 4-benzoyl-[1]naphthoic acid 

Relevant articles and documents

Palladium-Catalyzed Ligand-Controlled Regioselective Nucleophilic Aromatic Substitution of 1-(Chloromethyl)naphthalenes with Arylacetonitriles

The palladium-catalyzed reaction of 1-(chloromethyl)naphthalenes 1 with (hetero)arylacetonitriles 2 gives either para- or ortho-acylated naphthalenes (3 or 4) in good to high yields. The regioselectivity can be controlled by the ligand of a palladium catalyst. A sterically bulky ligand, tBuPPh2, affords para-acylated products 3, whereas a sterically less bulky ligand, Me2PPh, provides ortho-acylated products 4. Further, direct substitution product 5 at the benzylic position is not obtained essentially, although such a reaction at the benzylic position is favorable in ordinary nucleophilic substitutions. In this paper, it was revealed that the benzylpalladium intermediate could react through a different mode (η3-benzylpalladium intermediate or η1-benzylpalladium intermediate) in nucleophilic aromatic substitution. In addition to the interesting mechanistic aspect, the present reaction provides a facile synthetic method for a wide range of diaryl ketones, some of which are not easily available through the previously known procedures.

Synthesis and structural characterization of Pd(II) thiosemicarbazonato complex: Catalytic evaluation in synthesis of diaryl ketones from aryl aldehydes and arylboronic acids

A simple route to synthesize triphenylphosphinopalladium(II) thiosemicarbazonato complex has been described. Elemental analysis, spectral (IR, NMR) and single crystal X-ray diffraction techniques were employed for the complete characterization of the complex. The latter was found to be effective catalyst for carbon–carbon cross-coupling reaction of aryl- and heteroarylboronic acids with aromatic and heteroaromatic aldehydes to form the corresponding diaryl ketones. The influence of reaction parameters such as solvent, base, reaction temperature and catalyst loading was also investigated.

Gold-catalyzed reactions of enynals/enynones with norbornenes: Generation and trapping of cyclic o-quinodimethanes (o-QDMs)

Fan-like structures: An efficient AuIII-catalyzed method to generate the highly reactive cyclic o-quinodimethane (o-QDM) species from easily available enynals or enynones is presented (see scheme). This method produced a variety of structurally unique fan-like products with the advantages of mild reaction conditions, excellent diastereoselectivities, and high functional-group tolerance. Copyright