1166859-59-1Relevant articles and documents
Method for synthesizing chiral amine through palladium catalyzed asymmetric hydrogenolysis of racemic oxazirine
-
Paragraph 0048; 0049; 0050; 0051; 0052; 0053; 0054; 0055, (2017/01/02)
A catalysis system used in a method for synthesizing chiral amine through palladium catalyzed asymmetric hydrogenolysis of racemic oxazirine is a chiral diphosphine complex of palladium. The racemic substituted oxazirine is hydrogenolyzed to obtain corresponding chiral sulfonamide, and the enantiomeric excess can reach 99%. The method has the advantages of simple, practical and easy operation, commercially available catalyst and mild reaction conditions. The method for synthesizing the chiral sulfonamide through asymmetric hydrogenolysis also has the advantages of high antipodal selectivity, good yield, environmentally-friendly and atomically-economic reaction, and environmental protection.
Highly enantioselective synthesis of sultams via Pd-catalyzed hydrogenation
Yu, Chang-Bin,Wang, Da-Wei,Zhou, Yong-Gui
supporting information; experimental part, p. 5633 - 5635 (2009/12/08)
(Chemical Equation Presented) Using pd(cf3co2) 2/(S,S)-f-Binaphane as the catalyst, an efficient enantioselective synthesis of sultams was developed via asymmetric hydrogenation of the corresponding cyclic imines with high