117248-89-2

Basic information

• Product Name: (5-O-benzoyl-2,3-dideoxy-α-D-glycero-pentofuranosyl)cytosine
• CAS NO: 117248-89-2
• Molecular Weight: 315.329
• Mol File: 117248-89-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (5-O-benzoyl-2,3-dideoxy-α-D-glycero-pentofuranosyl)cytosine(CAS DataBase Reference)
• NIST Chemistry Reference: (5-O-benzoyl-2,3-dideoxy-α-D-glycero-pentofuranosyl)cytosine(117248-89-2)
• EPA Substance Registry System: (5-O-benzoyl-2,3-dideoxy-α-D-glycero-pentofuranosyl)cytosine(117248-89-2)

Safety Data

• Hazardous Substances Data: 117248-89-2(Hazardous Substances Data)

Upstream product

• 81252-26-8 1-chloro-5-O-benzoyl-2,3-dideoxy-D-glycero-pentofuranose 
• 18037-10-0 2,4-O,N-bis(trimethylsilyl)cytosine 
• 132575-43-0 5-O-benzoyl-2,3-dideoxy-D-glycero-pentofuranose 
• 117174-27-3 5-O-benzoyl-1-O-acetyl-2,3-dideoxy-D-glycero-pentofuranose 
• 32780-07-7 (S)-5-(benzoyloxymethyl)tetrahydrofuran-2-one 
• 121087-11-4 (S)-2-Benzyloxymethyl-5-bromo-tetrahydro-furan 
• 119555-42-9 O-benzoyl-2,3-dideoxy-2-fluoro-3-iodo-β-D-arabinofuranosyl)cytosine 
• 69123-99-5 1-(3-O-acetyl-5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)cytosine 
• 128495-99-8 1-(3,5-O-dibenzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)cytosine 
• 119555-41-8 1-<5-O-benzoyl-2-deoxy-2-fluoro-3-O-(methylsulfonyl)-β-D-arabinofuranosyl>cytosine 
• 119555-40-7 1-(5-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)cytosine 

Relevant articles and documents

STEREOSELECTIVITIES IN THE COUPLING REACTION BETWEEN SILYLATED PYRIMIDINE BASES AND 1-HALO-2,3-DIDEOXYRIBOSE

Coupling reactions between 1-chloro-2,3-dideoxyribose and silylated pyrimidines have been examined from the point of stereoselectivity.When the reaction was carried out in chloroform, the selectivity was in the anomeric ratio of α:β = 4:6.On the other hand, the presence of tertiary amine raises the selectivity to α:β = 3:7.

A NEW SYNTHESIS OF 2',3'-DIDEOXYNUCLEOSIDES FOR AIDS CHEMOTHERAPY

Dideoxynucleosides were prepared in high optical purity from L-glutamic acid.The condensation reactions between activated 2,3-dideoxypentofuranoses and silylated purines or pyrimidines afforded separable β/α mixtures of dideoxynucleosides.