117309-44-1 Usage
Description
[Benzenesulfonyl-(3-nitro-phenyl)-amino]-acetic acid is a complex chemical compound characterized by the presence of a sulfonyl group, a nitrophenyl group, an amino group, and an acetic acid group. This versatile molecule is known for its significant role in the pharmaceutical and chemical industries, particularly in the development of drugs with anticancer and antiviral properties. Its unique chemical structure allows it to serve as a common starting material for the synthesis of various pharmaceutical compounds and agrochemicals, as well as in the preparation of dyes, pigments, and fluorescent materials.
Uses
Used in Pharmaceutical Industry:
[Benzenesulfonyl-(3-nitro-phenyl)-amino]-acetic acid is used as a starting material for the synthesis of pharmaceutical compounds due to its diverse functional groups and reactivity. It plays a crucial role in the development of drugs with potential anticancer and antiviral properties, making it a valuable asset in the fight against various diseases.
Used in Agrochemical Industry:
In the agrochemical industry, [Benzenesulfonyl-(3-nitro-phenyl)-amino]-acetic acid is utilized as a starting material for the preparation of various agrochemicals. Its unique structure and functional groups contribute to the development of effective compounds for agricultural applications, such as pesticides and herbicides.
Used in Dye and Pigment Industry:
[Benzenesulfonyl-(3-nitro-phenyl)-amino]-acetic acid is employed as a key component in the preparation of dyes, pigments, and fluorescent materials. Its chemical structure allows for the creation of a wide range of colors and properties, making it an essential ingredient in the production of various dyes and pigments used in different industries, such as textiles, plastics, and printing.
Used in Organic Synthesis:
As a common starting material, [Benzenesulfonyl-(3-nitro-phenyl)-amino]-acetic acid is widely used in organic synthesis for the preparation of a variety of chemical compounds. Its versatile structure and functional groups enable chemists to synthesize a broad spectrum of molecules with diverse applications in various industries, including pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 117309-44-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,3,0 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 117309-44:
(8*1)+(7*1)+(6*7)+(5*3)+(4*0)+(3*9)+(2*4)+(1*4)=111
111 % 10 = 1
So 117309-44-1 is a valid CAS Registry Number.
117309-44-1Relevant articles and documents
N- and 2-Substituted N-(Phenylsulfonyl)glycines as Inhibitors of Rat Lens Aldose Reductase
DeRuiter, Jack,Borne, Ronald F.,Mayfield, Charles A.
, p. 145 - 151 (2007/10/02)
A variety of N-(phenylsulfonyl)-N-phenylglycines 5, N-(phenylsulfonyl)-2-phenylglycines 6, and N-(phenylsulfonyl)anthranilic acids 7 were prepared as analogues of the N-(phenylsulfonyl)glycine 1 aldose reductase inhibitors.In the rat lens assay, several derivatives of 5 display greater inhibitory activity than the corresponding glycines 1, suggesting that N-phenyl substitution enhances affinity for aldose reductase.Enzyme kinetic evaluations of the 4-benzoylamino analogues of 5 and 1 demonstrate that these compounds produce inhibition by the same mechanism.However, the significant differences in relative inhibitory potencies between compounds of series 5 and 1 may indicate that these compounds do not interact with the inhibitor binding site in precisely the same manner.Evaluation of the individual enantiomers of series 6 reveals that the S isomers are substantially more active than the corresponding R isomers.Also, with the exception of the naphthalene analogue 6n, the S stereoisomers of this series display greater inhibitory potencies than the glycines 1.The anthranilates 7 generally are less active than the glycines 1, demonstrating that direct incorporation of an aromatic ring in the glycine side chain may result in a decrease in affinity for aldose reductase.
