1174546-71-4Relevant articles and documents
Semisynthesis and pharmacological activities of Tetrac analogs: Angiogenesis modulators
Bridoux, Alexandre,Cui, Huadong,Dyskin, Evgeny,Yalcin, Murat,Mousa, Shaker A.
, p. 3259 - 3263 (2009)
Novel Tetrac analogs were synthesized and then tested. Anti-angiogenesis efficacy was carried out using the Chick Chorioallantoic Membrane (CAM) model and the mouse matrigel model for angiogenesis. Pharmacological activities showed Tetrac can accommodate numerous modifications and maintain anti-angiogenesis activity.
Uses of formulations of thyroid hormone antagonists and nanoparticulate forms thereof to increase chemosensivity and radiosensitivity in tumor or cancer cells
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Paragraph 0404, (2013/12/02)
Disclosed are methods of increasing the chemosensitivity of normal and/or chemoresistant tumor or cancer cells using thyroid hormone antagonists and/or nanoparticulate or polymeric forms thereof. Also disclosed are methods of increasing radiosensitivity of normal and/or radioresistant tumor or cancer cells using thyroid hormone antagonists and/or nanoparticulate or polymeric forms thereof.