1174586-22-1

Basic information

• Product Name: C₂₁H₃₉N₂O₂S⁽¹⁺⁾*I^(1-)
• Synonyms: C₂₁H₃₉N₂O₂S⁽¹⁺⁾*I^(1-)
• CAS NO: 1174586-22-1
• Molecular Weight: 510.523
• Mol File: 1174586-22-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₃₉N₂O₂S⁽¹⁺⁾*I^(1-)(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₃₉N₂O₂S⁽¹⁺⁾*I^(1-)(1174586-22-1)
• EPA Substance Registry System: C₂₁H₃₉N₂O₂S⁽¹⁺⁾*I^(1-)(1174586-22-1)

Safety Data

• Hazardous Substances Data: 1174586-22-1(Hazardous Substances Data)

Upstream product

• 10147-40-7 1-Dodecanesulfonyl chloride 
• 682343-24-4 C₂₀H₃₆N₂O₂S 
• 74-88-4 methyl iodide 

Relevant articles and documents

Design, synthesis and biological evaluation of novel aliphatic amido/sulfonamido-quaternary ammonium salts as antitumor agents

RhoB, one of the upstream signaling proteins of the phosphatidylinositol-3- kinase (PI3K)/Akt pathway, is frequently mutated in human cancer. Based on a piperazine alkyl derivative that induced apoptosis via up-regulation of RhoB, we synthesized novel aliphatic amido/sulfonamido-quaternary ammonium salts and evaluated their biological activities using an in vitro growth inhibition assay and RhoB promoter assay in human cancer cells. Compound 3a was the most promising anticancer agent in the series, based upon its potent growth inhibition via RhoB-mediated signaling. These novel aliphatic amido/sulfonamido-quaternary ammonium salts may be useful as a platform for development of anticancer chemotherapeutic agents.