117470-54-9Relevant articles and documents
Synthesis and Aggregation Behaviour of Chiral Cysteine Amphiphiles with s-Triazine as Connecting Unit
Staatz, Irina,Granzer, Ulrich H.,Blume, Alfred,Roth, Hermann J.
, p. 127 - 132 (2007/10/02)
Several homologous liposome building blocks 3 with L-cysteine as chiral hydrophilic head group are synthesized. s-Triazine serves as connecting unit between cysteine and the lipophilic alkyl chains.The phase transition temperatures of the lipids are determined by DSC or fluorescence anisotropy.It can be shown, that the relationship between nature and length of the chains and the phase transition temperature corresponds to that of phospholipids.Encapsulation experiments with ionic water-soluble dyes give some hints that the vesicles prepared in phosphate buffer (pH = 7.0) interact with cationic but not with anionic hydrophilic substances.