117756-01-1

Basic information

• Product Name: α-hydroxy-isobutyric acid o-anisidide
• CAS NO: 117756-01-1
• Molecular Weight: 209.245
• Mol File: 117756-01-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: α-hydroxy-isobutyric acid o-anisidide(CAS DataBase Reference)
• NIST Chemistry Reference: α-hydroxy-isobutyric acid o-anisidide(117756-01-1)
• EPA Substance Registry System: α-hydroxy-isobutyric acid o-anisidide(117756-01-1)

Safety Data

• Hazardous Substances Data: 117756-01-1(Hazardous Substances Data)

Upstream product

• 128965-64-0 2-(2-Methoxy-phenoxy)-2-methyl-propionamide 
• 90-04-0 2-methoxy-phenylamine 
• 80-55-7 ethyl 2-hydroxy-2,2-dimethylethanoate 

Downstream Products

• 107521-59-5 3-(2-methoxy-phenyl)-5,5-dimethyl-oxazolidine-2,4-dione 

Relevant articles and documents

The Conversion of Phenols to Primary and Secondary Aromatic Amines via a Smiles Rearrangement

The conversion of phenols to 2-aryloxy-2-methylpropanamides (1) and the Smiles rearrangement of these to N-aryl-2-hydroxy-2-methyl propanamides are described; hydrolysis of the latter compounds yields anilines.The scope and limitations of reaction are discussed.Routes, some involving α-lactams, from phenols to N-substituted derivatives of (1) have been developed.Under the conditions of the Smiles rearrangement these secondary 2-methylpropanamides can form directly anilides, N-alkylanilines, or benzoxazinones.