117858-54-5

Basic information

• Product Name: PAM3-CYS-ALA-GLY-OH
• Synonyms: S-[2,3-BIS(PALMITOYLOXY)-(2RS)-PROPYL]-N-PALMITOYL-(R)-CYS-ALA-GLY-OH;PALMITOYL-CYS((RS)-2,3-DI(PALMITOYLOXY)-PROPYL)-ALA-GLY-OH;PAM3-CYS-ALA-GLY-OH;N-palmitoyl-5,6-dipalmitoylcysteinyl-alanyl-glycine;PaM3Cys-Ala-Gly-OH, PaM3CAG;Pam3Cys-AG
• CAS NO: 117858-54-5
• Molecular Formula: C59H111N3O9S
• Molecular Weight: 1038.59
• Mol File: 117858-54-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 1051.3°Cat760mmHg
• Flash Point: 589.6°C
• Appearance: /
• Density: 1.001g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.488
• Storage Temp.: -15°C
• PKA: 3.34±0.10(Predicted)
• CAS DataBase Reference: PAM3-CYS-ALA-GLY-OH(CAS DataBase Reference)
• NIST Chemistry Reference: PAM3-CYS-ALA-GLY-OH(117858-54-5)
• EPA Substance Registry System: PAM3-CYS-ALA-GLY-OH(117858-54-5)

Safety Data

• Hazardous Substances Data: 117858-54-5(Hazardous Substances Data)

Usage

General Description

PAM3-CYS-ALA-GLY-OH is a synthetic chemical compound with potential immunostimulatory properties. It consists of a molecule of the triacylated lipopeptide PAM3 (Pamitoyl-XXX-XXX) linked to a peptide sequence containing the amino acids cysteine (CYS), alanine (ALA), and glycine (GLY), and terminating with an alcohol group (OH). PAM3-CYS-ALA-GLY-OH has been studied for its ability to activate the immune system and stimulate the production of pro-inflammatory cytokines, such as TNF-alpha and IL-1. PAM3-CYS-ALA-GLY-OH is being investigated for its potential use as an adjuvant in vaccines, and as a tool for studying the immune response to bacterial infection.

InChI:InChI=1/C59H111N3O9S/c1-5-8-11-14-17-20-23-26-29-32-35-38-41-44-54(63)62-53(59(69)61-51(4)58(68)60-47-55(64)65)50-72-49-52(71-57(67)46-43-40-37-34-31-28-25-22-19-16-13-10-7-3)48-70-56(66)45-42-39-36-33-30-27-24-21-18-15-12-9-6-2/h51-53H,5-50H2,1-4H3,(H,60,68)(H,61,69)(H,62,63)(H,64,65)/t51-,52?,53-/m0/s1