118091-50-2

Basic information

• Product Name: Phenol, 2,4-dibromo-6-[[[2-(dimethylamino)ethyl]imino]methyl]-
• CAS NO: 118091-50-2
• Molecular Formula: C11H14Br2N2O
• Molecular Weight: 350.053
• Mol File: 118091-50-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Phenol, 2,4-dibromo-6-[[[2-(dimethylamino)ethyl]imino]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2,4-dibromo-6-[[[2-(dimethylamino)ethyl]imino]methyl]-(118091-50-2)
• EPA Substance Registry System: Phenol, 2,4-dibromo-6-[[[2-(dimethylamino)ethyl]imino]methyl]-(118091-50-2)

Safety Data

• Hazardous Substances Data: 118091-50-2(Hazardous Substances Data)

Upstream product

• 90-59-5 3,5-Dibromosalicylaldehyde 
• 108-00-9 N,N-dimethylethylenediamine 

Downstream Products

• 1613543-80-8 C₅₄H₇₀Br₄N₄O₄ 
• 1613543-74-0 C₁₁H₁₆Br₂N₂O 

Relevant articles and documents

Synthesis, crystal structures and xanthine oxidase inhibitory activities of two copper(II) complexes with Schiff bases

Two azido-coordinated Schiff base Cu(II) complexes with the formulae [Cu(L1)(N3)]-MeOH and [Cu(L2)(μ1,1-N 3)]n, where L1 is the deprotonated form of 2-chloro-2-[(2- ethylaminoethylimino)methyl]phenol, and L2 is

Synthesis, molecular docking and biological evaluation of Schiff base transition metal complexes as potential urease inhibitors

Six transition metal compounds of Schiff base ligands were evaluated for the inhibitory activity on jack bean urease, of which compounds 2-6 were determined by single crystal X-ray analysis. It was found that copper(II) complexes 1 and 4 showed strong inhibitory activity against jack bean urease (IC50 = 0.52 and 0.46 μM), compared with acetohydroxamic acid (IC50 = 42.12 μM) as a positive reference. Cobalt(II), nickel(II) and zinc(II) compounds also exhibited potent inhibitory activity (IC 50 = 3.88-25.20 μM). A docking analysis using the AUTODOCK 4.0 program could explain the inhibitory activities of 1 and 4 against urease.