118286-11-6

Basic information

• Product Name: Acetic acid, (diphenylmethoxy)-, ethyl ester
• CAS NO: 118286-11-6
• Molecular Formula: C17H18O3
• Molecular Weight: 270.328
• Mol File: 118286-11-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Acetic acid, (diphenylmethoxy)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, (diphenylmethoxy)-, ethyl ester(118286-11-6)
• EPA Substance Registry System: Acetic acid, (diphenylmethoxy)-, ethyl ester(118286-11-6)

Safety Data

• Hazardous Substances Data: 118286-11-6(Hazardous Substances Data)

Upstream product

• 1204-50-8 benzhydrol sodium salt 
• 105-36-2 ethyl bromoacetate 
• 91-01-0 1,1-Diphenylmethanol 
• 623-73-4 diazoacetic acid ethyl ester 
• 623-50-7 ethyl 2-hydroxyacetate 

Downstream Products

• 26926-47-6 2-diphenylmethoxyethanol 
• 21409-25-6 Acetic acid,2-(diphenylmethoxy) 
• 18552-75-5 benzhydryloxy-acetic acid amide 
• 736933-40-7 (2S)-2-benzhydryloxy-1-(2,5-dimethoxy-phenyl)-hept-4-en-1-one 

Relevant articles and documents

Supramolecularly regulated copper-bisoxazoline catalysts for the efficient insertion of carbenoid species into hydroxyl bonds

The catalytic insertion of copper carbenoids into O-H bonds affords synthetically useful α-alkyl/aryl-α-alkoxy/aryloxy derivatives. Herein, the design, preparation and application of supramolecularly regulated copper(i) complexes of bisoxazoline ligands is reported. We have demonstrated that the catalytic performance of these systems can be modulated by the use of an external molecule (i.e.the regulation agent), which interacts with a polyethyleneoxy chain on the ligand (i.e.the regulation site)viasupramolecular interactions. This approach has been applied to an array of structurally diverse alcohols (cycloalkyl, alkyl and aryl derivatives). Moreover, we have used this methodology to synthesise advanced synthetic intermediates of biologically relevant compounds.

InCl3 catalyzed carbene insertion into O-H bonds: Efficient synthesis of ethers

An efficient InCl3 mediated insertion of the carbene fragment (:CHCO2Et), generated in situ from ethyl diazoacetate into O-H bond of a series of saturated and unsaturated alcohols under mild conditions has been developed to afford the corresponding ethers as exclusive products in good to high yields (70-95%) and in shorter reaction times. In the case of unsaturated alcohols, the reaction proceeded with unprecedented selectivity resulting in ethers as the only products and in high yields.

HETEROCYCLIC AMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS

Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type or T-type calcium channel activity are disclosed. Specifically, a series of heterocyclic amides are disclosed of the general formula (I) where Z is N or CHNR2 and X is NR2, O, S, S=O or SO2. Among other definitions for R, R1, W and Y, the compounds of formula (1) are further characterized by at least one of W or Y being CR3Ar2 where Ar is an aromatic or heteroaromatic ring (for example, where W or Y is a benzhydryl moiety).