118684-13-2 Usage
Description
4-BROMOMETHYL-3-METHOXYBENZOIC ACID is an organic compound characterized by its bromomethyl and methoxy groups attached to a benzoic acid structure. It is a white crystalline solid with potential applications in the pharmaceutical industry due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
4-BROMOMETHYL-3-METHOXYBENZOIC ACID is used as a reactant for the preparation of mifepristone analogs, which are liver-targeted glucocorticoid receptor antagonists. These analogs have potential therapeutic applications in treating various conditions by modulating the activity of glucocorticoid receptors in the liver.
Check Digit Verification of cas no
The CAS Registry Mumber 118684-13-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,6,8 and 4 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 118684-13:
(8*1)+(7*1)+(6*8)+(5*6)+(4*8)+(3*4)+(2*1)+(1*3)=142
142 % 10 = 2
So 118684-13-2 is a valid CAS Registry Number.
118684-13-2Relevant articles and documents
Identification of diamino chromone-2-carboxamides as MCHr1 antagonists with minimal hERG channel activity
Judd, Andrew S.,Souers, Andrew J.,Wodka, Dariusz,Zhao, Gang,Mulhern, Mathew M.,Iyengar, Rajesh R.,Gao, Ju,Lynch, John K.,Freeman, Jennifer C.,Falls, H. Douglas,Brodjian, Sevan,Dayton, Brian D.,Reilly, Regina M.,Gintant, Gary,Limberis, James T.,Mikhail, Ann,Leitza, Sandra T.,Houseman, Kathryn A.,Diaz, Gilbert,Bush, Eugene N.,Shapiro, Robin,Knourek-Segel, Victoria,Hernandez, Lisa E.,Marsh, Kennan C.,Sham, Hing L.,Collins, Christine A.,Kym, Philip R.
, p. 2365 - 2371 (2008/02/01)
A series of potent 2-carboxychromone-based melanin-concentrating hormone receptor 1 (MCHr1) antagonists were synthesized and evaluated for hERG (human Ether-a-go-go Related Gene) channel affinity and functional blockade. Basic dialkylamine-terminated anal
