1193092-68-0

Basic information

• Product Name: (Z)-2-bromo-1-phenylhex-1-en-5-yn-3-ol
• Synonyms: (Z)-2-bromo-1-phenylhex-1-en-5-yn-3-ol
• CAS NO: 1193092-68-0
• Molecular Weight: 251.123
• Mol File: 1193092-68-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (Z)-2-bromo-1-phenylhex-1-en-5-yn-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-bromo-1-phenylhex-1-en-5-yn-3-ol(1193092-68-0)
• EPA Substance Registry System: (Z)-2-bromo-1-phenylhex-1-en-5-yn-3-ol(1193092-68-0)

Safety Data

• Hazardous Substances Data: 1193092-68-0(Hazardous Substances Data)

Upstream product

• 33603-90-6 (2Z)-2-bromo-3-phenyl-2-propenal 
• 106-96-7 propargyl bromide 

Relevant articles and documents

PtI2-catalyzed cyclization of 3-acyloxy-1,5-enynes with the elimination of HOAc and a benzyl shift: Synthesis of unsymmetrical m-terphenyls

A novel cyclization of 3-acyloxy-1,5-enynes is developed in the presence of PtI2 for the synthesis of substituted unsymmetrical m-terphenyls in good to excellent yields. Two unique steps are involved in this transformation, which includes the elimination of HOAc and benzyl group migration. DFT calculations indicated that the rate-determining step is the migration of the benzylic carbocation to form a zwitterionic intermediate followed by the elimination of HOAc. The subsequent cyclopropanation of the zwitterionic intermediate is the regioselectivity-determining step.