1195-46-6

Basic information

• Product Name: Phenol, 4-(ethylthio)-
• Synonyms: Aethyl-(4-hydroxy-phenyl)-sulfid;4-ethylsulfanyl-phenol;4-Aethylmercapto-phenol;p-ethylthiophenol;4-Hydroxy-1-aethylmercapto-benzol
• CAS NO: 1195-46-6
• Molecular Formula: C8H10OS
• Molecular Weight: 154.233
• Mol File: 1195-46-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Phenol, 4-(ethylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-(ethylthio)-(1195-46-6)
• EPA Substance Registry System: Phenol, 4-(ethylthio)-(1195-46-6)

Safety Data

• Hazardous Substances Data: 1195-46-6(Hazardous Substances Data)

Upstream product

• 637-89-8 4-sulfanylphenol 
• 75-03-6 ethyl iodide 
• 1234217-82-3 4,4-bis(ethylthio)cyclohexa-2,5-dienone 
• 123-30-8 4-amino-phenol 
• 696-63-9 4-Methoxybenzenethiol 
• 156-43-4 4-Ethoxyaniline 
• 1117-96-0 Diazoethan 
• 1496-75-9 Ethanesulfenyl chloride 
• 108-95-2 phenol 
• 7205-58-5 ethyl (4-methoxyphenyl) sulfide 
• 74-96-4 ethyl bromide 

Downstream Products

• 91011-43-7 Methyl-phosphonothioic acid O-(4-ethylsulfanyl-phenyl) ester O-methyl ester 
• 945531-77-1 ezutromid 
• 84996-11-2 4-(ethylsulfonyl)-2-nitro-phenol 
• 859537-79-4 4-hydroxy-phenyl-ethylsulfone 
• 36116-16-2 p-Ethylsulfonylphenyl-methansulfonat 
• 36116-17-3 p-Ethylsulfinylphenyl-methansulfonat 
• 36089-94-8 C₁₄H₁₃NO₅S 
• 36089-82-4 C₁₄H₁₃NO₄S 
• 102455-00-5 1,4-bis-(4-ethanesulfonyl-phenoxy)-butane 
• 939980-70-8 2-[4-(ethylthio)phenoxy]acetohydrazide 

Relevant articles and documents

Synthesis process of ezutromid

The invention discloses a synthesis process of ezutromid, and relates to the field of drug synthesis. 4-mercaptophenol and an ethyl halide are taken as raw materials, a compound 2 is prepared, then acompound 3 is prepared through nitration, a compound 4 o

The influence of electronic perturbations on the Sulfur-Fluorine Gauche Effect Dedicated to Prof. Dr. Antonio Togni on the occasion of his 60th birthday.

Herein, a solution phase NMR conformer population analysis is employed to probe the effect of remote electronic perturbations on the conformational equilibria of a series of para-substituted β-fluorosulfides (1), sulfoxides (2) and sulfone derivatives (3). Conformations that allow for stabilizing stereoelectronic (σC-H → σ?C-F) and electrostatic (Fδ-...Sδ+) interactions predominate: this is consistent with the Sulfur-Fluorine Gauche Effect. The molar fractions (χ) of the two possible gauche conformers correlate linearly with the electron-withdrawing aptitude of the para-substituent, rendering the system ideally suited for a Hammett-type analysis. Despite the clear influence that the remote para-substituents have on conformer population, this is superseded by the oxidation state on sulfur (II, IV, VI), where an increased preference for the gauche conformer follows the trend: sulfide sulfone sulfoxide. It is envisaged that this proof of concept in controlling conformer population, either by proximal (oxidation state) or remote tuning (para-substituent), will find application in molecular design.

Chemoselectivity as a delineator of cuprate structure in Catalytic 1,4-Addition of Diorganozinc reagents to michael acceptors

Reaction of the cyclic thioacetal (RS)2CHCHO [R = 1/2x-(CH 2)3] with HCCCOMe, followed by treatment with TsCl/DABCO (Ts = tosyl, DABCO= 1,4-diazabicyclo[2.2.2]octane) affords the mono-protected 1,4-benzoquinone dithioaceta