1195768-24-1

Basic information

• Product Name: 3-(2,5-Difluorobenzenesulfonylamino)-2-fluorobenzoic acid methyl ester
• Synonyms: 3-(2,5-Difluorobenzenesulfonylamino)-2-fluorobenzoic acid methyl ester
• CAS NO: 1195768-24-1
• Molecular Weight: 345.299
• Mol File: 1195768-24-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(2,5-Difluorobenzenesulfonylamino)-2-fluorobenzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,5-Difluorobenzenesulfonylamino)-2-fluorobenzoic acid methyl ester(1195768-24-1)
• EPA Substance Registry System: 3-(2,5-Difluorobenzenesulfonylamino)-2-fluorobenzoic acid methyl ester(1195768-24-1)

Safety Data

• Hazardous Substances Data: 1195768-24-1(Hazardous Substances Data)

Upstream product

• 161957-56-8 3-bromo-2-fluorobenzoic acid 
• 437-86-5 2-fluoro-3-nitrotoluene 
• 1042055-86-6 methyl 3-((tert-butoxycarbonyl)amino)-2-fluorobenzoate 
• 946126-94-9 2-fluoro-3-nitrobenzoic acid methyl ester 
• 206551-41-9 2-fluoro-3-bromobenzoic acid methyl ester 
• 1195768-18-3 3-amino-2-fluorobenzoic acid methyl ester 
• 26120-86-5 2,5-difluorobenzenesulfonyl chloride 
• 914223-43-1 3-amino-2-fluoro benzoic acid 
• 317-46-4 2-fluoro-3-nitro-benzoic acid 

Downstream Products

• 1195768-25-2 N-{3-[2-(2-chloropyrimidin-4-yl)-acetyl]-2-fluoro-phenyl}-2,5-difluorobenzene-sulfonamide 
• 1309431-16-0 2,5-difluoro-N-(2-fluoro-3-hydroxymethyl-phenyl)-benzenesulfonamide 
• 1309431-17-1 2,5-difluoro-N-(2-fluoro-3-formyl-phenyl)-benzenesulfonamide 

Relevant articles and documents

N-(3-(5-(PYRIMIDIN-4-YL)THIAZOL-4-YL)PHENYL)SULFONAMIDE COMPOUNDS AND THEIR USES AS BRAF INHIBITORS

The present invention relates to N-(3-(5-(pyrimidin-4-yl)thiazol-4-yl)phenylsulfonamide compounds which are useful as inhibitors of protein kinases, more specifically BRAF or mutant forms thereof, to pharmaceutical composition comprising such compounds, and to uses of such compounds in the treatment or prevention of diseases associated with deregulated protein kinase activity, such as cancer.

Benzene Sulfonamide Thiazole and Oxazole Compounds

The present invention provides thiazole sulfonamide and oxazole sulfonamide compounds, compositions containing the same, as well as processes for the preparation and methods for their use as pharmaceutical agents.