1196870-93-5

Basic information

• Product Name: 5'-O-dimethoxytritylthymidine-3'-O-(2-oxo-1,3,2-dithiaphospholane)
• Synonyms: 5'-O-dimethoxytritylthymidine-3'-O-(2-oxo-1,3,2-dithiaphospholane)
• CAS NO: 1196870-93-5
• Molecular Weight: 682.755
• Mol File: 1196870-93-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5'-O-dimethoxytritylthymidine-3'-O-(2-oxo-1,3,2-dithiaphospholane)(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-dimethoxytritylthymidine-3'-O-(2-oxo-1,3,2-dithiaphospholane)(1196870-93-5)
• EPA Substance Registry System: 5'-O-dimethoxytritylthymidine-3'-O-(2-oxo-1,3,2-dithiaphospholane)(1196870-93-5)

Safety Data

• Hazardous Substances Data: 1196870-93-5(Hazardous Substances Data)

Upstream product

• 220063-81-0 1-[(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-([1,3,2]dithiaphospholan-2-yloxy)-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 

Downstream Products

• 118149-31-8 C₄₃H₄₇N₄O₁₄PS 

Relevant articles and documents

Studies of asymmetric induction in the synthesis of dinucleoside phosphorothioates from 2-oxo-1,3,2-dithiaphospholane nucleoside derivatives

The nucleoside derivatives, containing at 3'-O or 5'-O-position 2-oxo-1,3,2-dithiaphospholane function were found to react in the presence of DBU with a hydroxyl group of appropriately protected nucleosides to yield, after deprotection, dinucleoside phosphorothioates in moderate yields. An asymmetric induction connected with the formation of new chiral phosphorothioate center has been examined.