120-66-1Relevant articles and documents
Selective Preparation. 38. A Convenient Preparation of 2-(Acylamino)biphenyls and N-Acetylaniline Derivatives Using the tert-Butyl Group as a Positional Protective Function
Tashiro, Masashi,Fukuda, Yasuhisa,Yamato, Takehiko
, p. 1927 - 1928 (1983)
-
Late-Stage Diversification of Biarylphosphines through Rhodium(I)-Catalyzed C-H Bond Alkenylation with Internal Alkynes
Zhang, Zhuan,Cordier, Marie,Dixneuf, Pierre H.,Soulé, Jean-Fran?ois
, p. 5936 - 5940 (2020)
We report herein P(III)-directed C-H bond alkenylation of (dialkyl)- and (diaryl)biarylphosphines using internal alkynes. Chloride-free [Rh(OAc)(COD)]2 acts as a better catalyst than commercially available [RhCl(COD)]2. Conditions were developed to control the mono- and difunctionalization depending on the alkyne stoichiometry. One of these novel bisalkenylated (dialkyl)biarylphosphines was employed for the preparation of a palladium(II) complex, and some of these functionalized ligands outperformed their corresponding unfunctionalized phosphines in Pd-catalyzed amidation with sterically hindered aryl chlorides.
Ortho-Alkylation of Acetanilides Using Alkyl Halides and Palladium Acetate
Tremont, Samuel J.,Rahman, Hayat Ur
, p. 5759 - 5760 (1984)
-
Sunlight-assisted decomposition of cephalexin by novel synthesized NiS-PPY-Fe3O4 nanophotocatalyst
Torki,Faghihian
, p. 49 - 59 (2017)
In this research, the catalytic performance of NiS and NiS immobilized into the matrix of magnetite polypyrrole core/shell (Fe3O4@PPY) for degradation of cephalexin was investigated. After characterization, by FTIR, TG, XRD, VSM, DRS, PL, Brunauer–Emmett–Teller (BET), TEM and SEM techniques, the photocatalysts were used for degradation of a pharmaceutical pollutant; cephalexin under UV and sunlight irradiations. The results indicated that application of PPY-Fe3O4 as the catalyst supports significantly enhanced the photocatalytic activity of NiS. The degradation efficiency obtained by NiS-PPY-Fe3O4 was higher than the value obtained by NiS alone. Moreover, by use of the support, a significant red shift was occurred on the band gap energy of NiS resulting higher degradation of the pollutant under sunlight irradiation. Paramagnetic nature of the NiS-PPY-Fe3O4 photocatlyst enabled effective separation of the used catalysts from the reaction solution with the aid of an external magnetic field and avoiding the tedious filtration or centrifugation. Upon regeneration, the photocatalyst retained most of its initial efficiency. Addition of H2O2 to the photocatalyst mixture had an enhancing effect on the cephalexin degradation. The photodegradation products were identified by GC–MS technique.
Highly Efficient and Practical Synthesis of the Key Intermediate of Telmisartan
Zhao, Jianhong,Xiong, Yicheng,Yang, Wu-Lin,Yang, Fan,Jin, Yu
, p. 1022 - 1027 (2021/04/12)
We reported herein an efficient and practical method to access 1,7′-dimethyl-2′-propyl-2,5′-bi(1H-benzimidazole) 1, a key intermediate for the synthesis of telmisartan. The synthetic route was based on readily available o-methylaniline as the starting material, and the target product 1 was prepared through a six-step process, including amidation, formylation, cyclization, hydrolysis, amidine, and oxidation. The overall yield for the preparation of 1 was 51.5% on the 100 g scale, with a purity of 99.91%. The salient features of this method include economic and easily available starting materials, operational simplicity, and environmentally friendly, which is suitable for the industrial production.
Preparation and catalytic evaluation of a palladium catalyst deposited over modified clinoptilolite (Pd&at;MCP) for chemoselective N-formylation and N-acylation of amines
Amirsoleimani, Mina,Khalilzadeh, Mohammad A.,Zareyee, Daryoush
, (2020/08/22)
Novel palladium nanoparticles stabilized by clinoptilolite as a natural inexpensive zeolite prepared and used for N-formylation and N-acylation of amines at room temperature at environmentally benign reaction conditions in good to excellent yields. Pd (II) was immobilized on the surface of clinoptilolite via facile multi-step amine functionalization to obtain a sustainable, recoverable, and highly active nano-catalyst. The structural and morphological characterizations of the catalyst carried out using XRD, FT-IR, BET and TEM techniques. Moreover, the catalyst is easily recovered using simple filtration and reused for 7 consecutive runs without any loss in activity.
