120049-04-9

Basic information

• Product Name: 2-Butenedioic acid, 2-(1H-imidazol-1-yl)-, bis(1,1-dimethylethyl) ester, (Z)-
• CAS NO: 120049-04-9
• Molecular Formula: C15H22N2O4
• Molecular Weight: 294.351
• Mol File: 120049-04-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Butenedioic acid, 2-(1H-imidazol-1-yl)-, bis(1,1-dimethylethyl) ester, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenedioic acid, 2-(1H-imidazol-1-yl)-, bis(1,1-dimethylethyl) ester, (Z)-(120049-04-9)
• EPA Substance Registry System: 2-Butenedioic acid, 2-(1H-imidazol-1-yl)-, bis(1,1-dimethylethyl) ester, (Z)-(120049-04-9)

Safety Data

• Hazardous Substances Data: 120049-04-9(Hazardous Substances Data)

Upstream product

• 66086-33-7 Di-tert-butyl acetylenedicarboxylate 
• 55628-82-5 1-(Phenylacetyl)imidazole 

Relevant articles and documents

Regiospecific Synthesis, Structure, and Fluorescence Properties of Highly Substituted Imidazopyridines and Pyridobenzimidazoles

1-(Arylacetyl)imidazoles 1 react with acetylenedicarboxylic esters to provide highly functionalized imidazopyridines 2 in up to 89percent yield.The scope and limitations of this novel condensation reaction have been investigated, and a mechanistic interpretation is presented.A strong effect on the yield of this reaction is observed for electron-donating and electron-withdrawing substituents in the para position of the aryl ring.Moreover, the transformation is shown to proceed in a regiospecific manner starting with 4,5-unsymmetrically substituted 1-(arylacetyl)imidazoles (1d-g) and is extended to the synthesis of the corresponding pyridobenzimazoles 12.The crystal structure of derivative 2a has been determined by X-ray analysis.Imidazopyridines 2 and pyridobenzimidazoles 12, obtained by this procedure, are highly fluorescent in the visible region with characteristically large Stokes shifts.