1202-71-7 Usage
Description
1-Azacyclododecan-2-one, also known as 1,12-Cyclododecanedione, is a heterocyclic compound with the molecular formula C12H23NO. It is a cyclic amide derivative of 1,12-dodecanediamine, characterized by its white solid appearance and a melting point of 98-100 °C. This versatile chemical is soluble in both water and organic solvents, making it a valuable building block in organic synthesis for the creation of biologically active compounds, pharmaceuticals, and agrochemicals. Its utility extends to the production of polymers and as a reagent in various organic reactions, as well as serving as a complexing agent in metal ion coordination chemistry.
Uses
Used in Organic Synthesis:
1-Azacyclododecan-2-one is used as a building block for the synthesis of biologically active compounds, which are essential in the development of new pharmaceuticals and agrochemicals. Its unique structure allows for the creation of a variety of complex molecules with potential therapeutic or pesticidal properties.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-Azacyclododecan-2-one serves as a key intermediate in the production of various drugs. Its ability to form stable complexes with metal ions makes it a valuable component in the design of metal-based pharmaceuticals, which can have applications in treating a range of diseases.
Used in Agrochemical Industry:
1-Azacyclododecan-2-one is utilized in the agrochemical industry for the synthesis of pesticides and other crop protection agents. Its role in creating stable and effective compounds contributes to the development of products that protect crops from pests and diseases, thereby ensuring food security.
Used in Polymer Production:
In the polymer industry, 1-Azacyclododecan-2-one is used in the synthesis of polymers with specific properties, such as enhanced stability, solubility, or reactivity. These polymers can be employed in various applications, including coatings, adhesives, and plastics.
Used as a Reagent in Organic Reactions:
1-Azacyclododecan-2-one acts as a reagent in a range of organic reactions, facilitating the formation of desired products with high yields and selectivity. Its versatility in participating in various reaction types, such as condensation, substitution, or rearrangement reactions, makes it a valuable tool in organic chemistry.
Used in Metal Ion Coordination Chemistry:
As a complexing agent, 1-Azacyclododecan-2-one is used in metal ion coordination chemistry to form stable complexes with metal ions. These complexes have potential applications in catalysis, sensing, and materials science, where their unique properties can be harnessed for various technological advancements.
Check Digit Verification of cas no
The CAS Registry Mumber 1202-71-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,0 and 2 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1202-71:
(6*1)+(5*2)+(4*0)+(3*2)+(2*7)+(1*1)=37
37 % 10 = 7
So 1202-71-7 is a valid CAS Registry Number.
1202-71-7Relevant articles and documents
A Deep Cavitand Templates Lactam Formation in Water
Mosca, Simone,Yu, Yang,Gavette, Jesse V.,Zhang, Kang-Da,Rebek, Julius
, p. 14582 - 14585 (2015)
Cyclization reactions are common processes in organic chemistry and show familiar patterns of reaction rates vs ring size. While the details vary with the nature of bond being made and the number of unsaturated atoms, small rings typically form quickly despite angle strain, medium size rings form very slowly due to internal strains, and large rings form slowly (when they form at all) because fewer and less probable conformations bring the ends of the substrate together. High dilution is commonly used to slow the competing bi- and higher molecular processes. Here we apply cavitands to the formation of medium size lactams from ω-amino acids in aqueous (D2O) solution. The cavitands bind the amino acids in folded conformations that favor cyclization by bringing the ends closer together. Yields of a 12-membered lactam are improved 4.1-fold and 13-membered lactam 2.8-fold by the cavitand template. The results open possibilities for moving organic reactions into water even when the processes involve dehydration.
A novel synthetic route of fused tricyclic framework quinoline derivatives from readily available aliphatic amino carboxylic acid substrates
Mohammed, Shireen
, p. 611 - 617 (2019/06/07)
A novel and an efficient strategy of fused tricyclic quinoline heterocycle compounds from aliphatic amino carboxylic acid substrates was studied. The protocol here is proceed over main reaction processes including: cyclization, protection, amidine formation, further cyclization and finally coupling with boronic acid substrate through Suzuki reaction. These reactions afforded the corresponding products in high yields. Furthermore, all synthesized compounds were identified by spectral data.
RING CLOSING METATHESIS APPROACH TO PRODUCE PRECURSORS OF NYLON 11, 12, AND 13 FROM OLEIC ACID
-
, (2016/01/25)
Provided herein is a method of producing C11, C12, and C13 nylon precursors from oleic acid or esters of oleic acid, the method involving amide formation, ring-closing metathesis, and hydrogenation. Further provided are the products of the method described. Provided herein is a method for producing a lactam, the method comprising the steps of converting oleic acid or an ester of oleic acid into an amide having a general formula of H3C-(CH2)rCH=CH-(CH2)rCONR-(CH2)n-CH=CH2, wherein n is 1, 2, or 3, and R is either hydrogen or benzyl; subjecting the amide to a ring-closing metathesis reaction to produce an intermediate having a general formula of -(CH2)rCONR-(CH2) n-CH=CH2-, wherein n is 1, 2, or 3, R is either hydrogen or benzyl, and both ends are connected to each other; and hydrogenating the intermediate to produce a saturated lactam. In certain embodiments, the saturated lactam has a formula of -NH-(CH2) 10-CO-.
