121013-78-3

Basic information

• Product Name: (R)-2-Phenylpropionsaeure-<(2R,3S)-tetrahydro-2-methylthiophen-3-yl>ester
• Synonyms: (R)-2-Phenylpropionsaeure-<(2R,3S)-tetrahydro-2-methylthiophen-3-yl>ester
• CAS NO: 121013-78-3
• Molecular Weight: 250.362
• Mol File: 121013-78-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-Phenylpropionsaeure-<(2R,3S)-tetrahydro-2-methylthiophen-3-yl>ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-Phenylpropionsaeure-<(2R,3S)-tetrahydro-2-methylthiophen-3-yl>ester(121013-78-3)
• EPA Substance Registry System: (R)-2-Phenylpropionsaeure-<(2R,3S)-tetrahydro-2-methylthiophen-3-yl>ester(121013-78-3)

Safety Data

• Hazardous Substances Data: 121013-78-3(Hazardous Substances Data)

Upstream product

• 121249-25-0 (2R,3S)-Tetrahydro-2-methylthiophen-3-ol 
• 36240-11-6 (R)-(-)-2-phenylpropionyl chloride 
• 66319-07-1 5-methyl-4-oxotetrahydro-3-thiophencarboxylic acid methyl ester 
• 74015-70-6 4,5-Dihydro-2-methylthiophen-3-(2H)-on 

Relevant articles and documents

Stereoisomeric Flavor Substances XXXI. - Tetrahydro-2-methylthiophen-3-ol - Structure and Properties of the Stereoisomers

Tetrahydro-2-methylthiophen-3-ol (6) has been synthesized and separated by liquid chromatography to yield cis(6a/6a') and trans isomers (6b/6b').Using (S)-tetrahydro-5-oxo-2-furancarboxylic acid chloride, 6a/6a' and 6b/6b' are transformed into the diastereomeric esters 7 - 10 which are separated by liquid chromatography.Hydrolysis of the esters yields the optically pure stereoisomers 6a, 6a', 6b, and 6b'.Absolute configuration and sensory characteristics of these stereoisomers are given.